Clinical Study of Huabi Yougui Granule on the Treatment of Liver and Kidney Deficiency Type of Lumbar Disc Herniation
Objective:To observe the clinical efficacy of Huabi Yougui granule of Qinggong orthopedic school on the treat-ment of lumbar disc herniation of liver and kidney deficiency type(inclined to Yang deficiency type)based on the theory of"Yang Hua Qi",and to evaluate its efficacy and safety.Methods:60 patients with lumbar disc herniation of liver and kidney deficiency were randomly divided into the traditional Chinese medicine(TCM)group and the control group.The patients in the TCM group were given Huabi Yougui granules,and the patients in the control group were given imrecoxib tablets.Visual analogue scale(VAS)score,Japanese orthopaedic association(JOA)score,TCM symptom grading quantitative table score,serum inflammatory factors(tumor necrosis factor-α(TNF-α),interleukin-6(IL-6))levels and clinical effica-cy were statistically analyzed.Results:After 2 and 4 weeks of treatment,VAS scores were decreased,JOA scores were increased,and TCM syndrome scores were decreased in the two groups.After 2 weeks of treatment,the improvement of VAS score and JOA score in the control group was better than that in the TCM group,and the improvement of TCM syn-drome score in the TCM group was better than that in the control group(P＜0.05).After 4 weeks of treatment,the improvement of VAS score,JOA score,TCM syndrome score and serum inflammatory factors in the TCM group were bet-ter than those in the control group(P＜0.05).During the treatment period,no adverse reactions such as allergic reactions and gastrointestinal symptoms were observed.Con-clusion:Huabi Yougui granule can significantly reduce waist and leg pain,improve the quality of life,and relieve inflam-matory response on the treatment of lumbar disc herniation with liver and kidney deficiency based on the theory of"Yang Hua Qi".
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