摘要
目的:探讨弹拨、牵引及松解三步疗法治疗对膝骨关节炎(KOA)患者膝关节疼痛、膝关节活动功能、关节液TNF-α及IL-1水平的影响.方法:选取2021年1月至2022年10月收治的膝骨关节炎患者100例,采用随机数字表法分为对照组和观察组(各50例).对照组患者给予洛索洛芬胶囊和硫酸氨基葡萄糖胶囊治疗;观察组患者采用弹拨、牵引及松解三步平衡法治疗.比较两组患者治疗前后视觉模拟量表(VAS)评分,西安大略和麦克马斯特大学(WOMAC)量表评分,关节液TNF-α和IL-1浓度变化及临床疗效.结果:治疗前,两组患者VAS评分、关节压痛、晨僵、关节活动度、关节肿胀、日常活动难度评分及TNF-α、IL-1浓度比较,差异无统计学意义(P＞0.05);治疗后,两组患者VAS评分、关节压痛、晨僵、关节活动度、关节肿胀、日常活动难度评分及TNF-α、IL-1浓度均明显降低,差异有统计学意义(P＜0.05),观察组患者治疗后VAS评分、关节压痛、晨僵、关节活动度、关节肿胀、日常活动难度评分及TNF-α、IL-1浓度均低于对照组患者,差异有统计学意义(P＜0.05);观察组患者总有效率96.00％高于对照组患者82.00％,差异有统计学意义(P＜0.05).结论:弹拨、牵引及松解三步疗法可显著缓解膝骨关节炎患者关节疼痛,改善膝关节活动功能,降低关节液中炎症程度,临床疗效满意.
Abstract
Objective:To explore the treatment of knee joint pain,knee joint mobility,and joint fluid TNF-α in patients with knee osteoarthritis(KOA)using the three-step balance method of spring,traction,and release the impact of IL-1 levels.Methods:100 KOA patients from January 2021 to October 2022 were selected and randomly divided into a control group and an observation group,with 50 patients in each group.The control group was treated with losoprofen capsules and glu-cosamine sulfate capsules.The observation group was treated with a three-step balance method of spring,traction,and re-lease,and the visual analogue scale(VAS)scores,Western Ontario and McMaster Universities(WOMAC)scale scores,and joint fluid TNF-α before and after treatment were compared between the two groups changes in IL-1 concentration and clinical efficacy.Results:Before treatment,both groups had VAS scores,joint tenderness,morning stiffness,joint range of motion,joint swelling,difficulty in daily activities scores,and TNF-α.There was no significant difference in IL-1 concen-tration(P＞0.05).After treatment,two groups of VAS scores,joint tenderness,morning stiffness,joint range of motion,joint swelling,difficulty in daily activities scores,and TNF-α.The concentration of IL-1 was significantly reduced in the observation group(P＜0.05).After treatment,patients in the observation group had VAS scores,joint tenderness,morn-ing stiffness,joint range of motion,joint swelling,difficulty score of daily activities,and TNF-α.The concentration of IL-1 was lower than that of the control group(P＜0.05).The total effective rate of 96.00％in the observation group was higher than 82.00％in the control group(P＜0.05).Conclusion:The three-step balance method of spring,traction,and re-lease can significantly alleviate joint pain,improve knee joint mobility,and reduce inflammation in joint fluid in KOA patients.The clinical efficacy is satisfactory.
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