Report of 30 Cases of Antibiotic-Loaded Bone Cement Coverage for the Treatment of Chronic Refractory Wounds
Objective:To investigate the efficacy of treatment of chronic refractory wounds with antibiotic-loaded bone ce-ment coverage.Methods:30 patients with chronic refractory wounds between January 2020 and January 2023 who were treated with antibiotic-loaded bone cement therapy were selected for the study to evaluate its efficacy.Results:The final cure rate of the 30 patients included in the study was 21(70.00％),7(23.30％)effective and 2(6.67％)ineffective,that is,the overall efficacy was 93.30％.The mean number of debridements was(1.63±1.13)times,and there were differ-ences in leukocyte count,C-reactive protein and erythrocyte sedimentation rate before surgery and 3 weeks after surgery(P＜0.05).Conclusion:The efficacy of antibiotic-loaded bone cement coverage in the treatment of chronic refractory wounds is accurate,provides effective control of wound infection and has a satisfactory therapeutic effect.
antibiotic-loaded bone cementchronic refractory woundsinfectionrifampicinvancomycin
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