Study on the Correlation of Bone Metabolic Markers in Different Kidney Deficiency Syndrome Types of Postmenopausal Osteoporosis
Objective:To explore the serological differences between different types of evidence and provide an objective basis for the analysis of Chinese medicine evidence in postmenopausal osteoporosis patients by analyzing the serum indexes of postmenopausal osteoporosis patients with different kidney deficiency types.Methods:45-80 years old osteoporosis patients with menopause were selected from February 2021 to January 2022 with two syndrome types of liver-kidney Yin deficiency and kidney Yang deficiency.Bone mineral density(BMD),general clinical features and bone metabolism markers were collected,and the differences of indicators among different syndrome types were compared.Results:Among the 93 patients,53 were in the kidney Yang deficiency syndrome group and 40 were in the liver-kidney Yin deficiency syndrome group.It was found that the β-CTX level of patients with kidney Yang deficiency was significantly higher than that of the liver-kidney Yin deficiency group after statistical analysis of one-to-one matching of age and body mass index(BMI)(P<0.05),and the serum parathyroid hormone(PTH)level of patients of the liver-kidney Yin deficiency group was signifi-cantly higher than that of the kidney Yang deficiency group(P<0.05),both differences were statistically significant.Con-clusion:In postmenopausal osteoporosis,the level of bone resorption may be higher in patients with kidney Yang deficien-cy,whereas patients with live-kidney Yin deficiency are more predisposed to altered parathyroid pathology.
postmenopausal osteoporosisliver-kidney Yin deficiencykidney Yang deficiencysyndrome