Application Study of Periosteal Distraction Surgery Combined with Antibiotic Bone Cement on the Treatment of Diabetes Foot
Objective:To observe the efficacy of periosteal distraction surgery combined with antibiotic bone cement in trea-ting diabetes foot(DF).Methods:A total of 66 patients with DF were grouped into two groups using a random number ta-ble method.The 33 cases in control group underwent periosteal distraction surgery,while 33 cases in observation group underwent periosteal distraction surgery combined with antibiotic bone cement.Surgical indicators,wound healing,toe blood oxygen saturation(SaO2),foot temperature,ankle brachial index,degree of pain,lower limb nerve conduction func-tion,inflammatory factors,and complications were compared.Results:There was no statistically obvious difference in sur-gical time,intraoperative blood transfusion volume,and amputation rate between observation group and control group(P＞0.05);the wound healing rate in observation group were higher than that in control group(P＜0.05),and the ulcer healing time and bone window healing time in the observation group were shorter than those in control group(P＜0.05).At 12 weeks after surgery,the toe SaO2,foot temperature,and ankle brachial index of both groups were higher than before surgery(P＜0.05),and observation group were higher than control group(P＜0.05).At 12 weeks after surgery,the vis-ual analogue scale(VAS)scores of both groups were lower than before surgery(P＜0.05),and scores of observation group were smaller than control group(P＜0.05).After surgery,the sensory conduction velocity of the common peroneal nerve and the tibial nerve in both groups were higher than before surgery(P＜0.05),and observation group were higher than control group(P＜0.05).After surgery,the lev-els of interleukin-6(IL-6)and IL-17 in both groups were lower than before surgery(P＜0.05),and observation group were smaller than control group(P＜0.05).There was no statistically significant difference in the incidence of complica-tions between the two groups(P＞0.05).Conclusion:The combination of periosteal distraction surgery and antibiotic bone cement can improve the wound healing rate,shorten the ulcer healing time and bone window healing time,improve toe SaO2,foot temperature,ankle brachial index,lower limb nerve conduction function,alleviate pain,reduce inflammatory fac-tors,and do not increase the occurrence of complications in DF patients.
periosteal distraction surgeryantibiotic bone cementdiabetic footsurgical indicatorstoe blood oxygen saturation
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