The Correlation of Serum C-terminal Telopeptide of Type Ⅰ Collagenβ-crosslinked Peptide Level in the Occurrence of Osteonecrosis of the Femoral Head and Bone Cystic Degeneration
Objective:To investigate the relationship between bone cystic degeneration of femoral head and serum β-CTx of type Ⅰ collagen in patients with osteonecrosis of the femoral head(ONFH).Methods:A total of 263 hips of 180 patients with ONFH who were admitted from May 2023 to December 2023 were collected.According to the presence or absence of bone cystic degeneration on X-ray and CT images,the patients were divided into cystic degeneration group and non-cystic degeneration group,and the differences in blood β-CTx levels between the two groups were compared.Results:There were 86 patients in the cystic degeneration group,63 males and 23 females,with(40.84±12.72)years old on average and an average course of(7.85±2.47)months.There were 94 patients in the non-cystic degeneration group,64 males and 30 females,with an average age of(44.09±12.85)years old and an average course of(7.85±3.15)months.Serum β-CTx in patients with cystic degeneration(0.86±0.37)ng/mL was significantly higher than that in patients without cystic degeneration(0.52±0.20)ng/mL,and the difference was statistically significant(F=26.631,P＜0.001).Conclusion:Serum β-CTx level was significantly higher in patients with osteonecrosis combined with bone cystic degeneration than in patients without bone cystic degeneration,suggesting that rapid bone resorption may be one of the important reasons for the occurrence of bone cystic degeneration.
osteonecrosis of femoral headbone cystic degenerationβ-CTx of type Ⅰ collagen
万方数据
维普
