Research Progress on Influencing Factors of Platelet Rich Plasma in the Treatment of Knee Osteoarthritis
Intraarticular injection of platelet rich plasma(PRP)was one of the new conservative treatments for knee oste-oarthritis(KOA).PRP was considered to have the effect of repairing cartilage because it contains a large amount of growth factors.Nowadays,it was widely used in the treatment of degenerative diseases of bone and cartilage.However,there were various methods for preparing,storing,and injecting PRP in clinically.Different methods lead to certain differ-ences in clinical efficacy.Therefore,this review analyzed the factors influencing the efficacy of PRP in the treatment of KOA from the aspects of composition,storage and use,in order to provide reference for the clinical application of PRP.