Correlation Study on the Chinese Medicine Syndrome Characteristics and Prognosis in Patients with Sepsis-associated Acute Kidney Injury
Objective:To investigate the correlation between Chinese medicine syndrome differentiation and prognosis in patients with sepsis-associated acute kidney injury(SA-AKI).Methods:A retrospective study was conducted on patients who were admitted to the emergency ward of Guangdong Provincial Hospital of Chinese Med-icine.SA-AKI patients from June 2018 to May 2023 were screened and a total of 160 SA-AKI patients were se-lected based on the inclusion and exclusion criteria.The general information,clinical diagnosis details,laboratory test results,Sequential Organ Failure Assessment(SOFA)scores,Acute Physiology and Chronic Health EvaluationⅡ(APACHE Ⅱ)scores,underlying conditions,infection sites on the day of admission,and 28 day mortality were collected.Results:Univariate regression analysis indicated that for patients with transient SA-AKI[OR=2.070,95％ CI(1.042-4.109)],patients with acute deficiency syndrome[OR=2.047,95％CI(1.065-3.935)],and patients in Kidney Disease:Improving Global Outcomes(KDIGO)stage[stage 2 OR=2.575,95％ CI(1.114-5.952);stage 3 OR=2.853,95％ CI(1.034-7.875)],persistent SA-AKI had an increased risk of death.The COX regression anal-ysis,including age,gender,SA-AKI type,KDIGO stage,and acute deficiency syndrome,was statistically significant(x2=13.305,P=0.038),acute deficiency syndrome had independent risk factors[OR=0.558,95％ CI(0.347-0.995),P=0.048].Conclusion:The root cause of SA-AKI is typically attributed to a deficiency of qi.To effec-tively treat this condition,a blend of western medicine and traditional Chinese practices is suggested.It is crucial to pay attention to reinforcing the healthy qi early and wholly,while also activating blood and resolving stasis,mov-ing qi and relaxing the bowels to prevent persistent SA-AKI and minimize the risk of mortality.
NETL
NSTL
万方数据
维普
