Syndrome Distribution Pattern of 135 Cases of Sepsis-induced Acute Lung Injury and Understanding of Traditional Chinese Medicine Diagnosis and Treatment Theory
Objective:To explore the distribution patterns and characteristics of traditional Chinese medicine syndromes in patients with sepsis-induced acute lung injury,and to provide a basis for clinical diagnosis and treat-ment based on syndrome differentiation.Methods:A retrospective study method was used to collect clinical data of patients with sepsis-induced acute.lung injury from the Affiliated Hospital of Shandong University of Tradition-al Chinese Medicine from January 2017 to December 2020.A traditional Chinese medicine(TCM)syndrome ques-tionnaire was designed,a database was established,and SPSS 26.0 software was used for statistical analysis.Results:The medical records of a total of 135 patients were collected,with an average age of(64.38±17.61)years,and the highest number of patients in the 61~80 age group;61% of the patients survived 28 days,with an average age of(57.78±17.86)years;the patients who died accounted for 39%,with an average age of(70.98± 17.37)years.The main basic diseases were hypertension,cardiovascular and cerebrovascular diseases,and diabe-tes.The number of cases with a single syndrome:heat toxin syndrome>phlegm heat syndrome>blood stasis syn-drome>fushi syndrome>qi deficiency syndrome>phlegm turbidity syndrome>yang deficiency syndrome>yin deficien-cy syndrome.The number of cases with composite syndrome:two types of composite syndrome>three types of com-posite syndrome>one type of composite syndrome.The most common combination of two syndromes was heat toxin syndrome+visceral syndrome,the most common combination of three syndromes was heat toxin syndrome+phlegm heat syndrome+visceral syndrome,and the most common one type was heat toxin syndrome.The number of cases of deficiency and excess syndrome:excess syndrome>mixed deficiency and excess syndrome>deficiency syndrome,while the survival rate was in the opposite order.Conclusion:The basic pathogenesis is pathogenic ex-cess,positive deficiency,and lung dysfunction.The pathological nature always belongs to the syndrome of excess in symptoms and deficiency in origin.Pathological factors include heat toxicity,phlegm,and blood stasis.The syn-drome types are mainly characterized by heat toxicity,phlegm turbidity,blood stasis,and visceral excess,with com-plex syndromes being common.The prognosis is poor due to the combination of deficiency and excess,especially the deficiency syndrome.The treatment should mainly focus on clearing heat,resolving phlegm,promoting blood circulation,and clearing the internal organs,supplemented by tonifying qi,warming yang,and nourishing yin.Elder-ly patients especially need to support the healthy qi.The condition is complex,and we should start from the over-all perspective,further grasp the evolution law of the entire process of the disease syndrome,and enrich and im-prove the syndrome differentiation system.
Sepsis-induced acute lung injurySyndromeClinical studyDiagnosis and treatment theory