Clinical Observation on the Treatment of Acute Ankle Sprain with Oral and External Application of Modified Shaoyao Gancao Decoction
Objective:To observe the clinical efficacy on the treatment of acute ankle sprain and safety with oral and external application of Modified Shaoyao Gancao Decoction.Methods:A total of 62 patients were ran-domly divided into two groups,with 32 cases in the study group and 30 cases in the control group.The control group was treated with loxoprofen sodium gel plaster,and the study group was treated with Modified Shaoyao Gan-cao Decoction for oral and external application.Both groups were treated for 14 days.The therapeutic effects,pain,ankle joint function,swelling,inflammatory factors before and after 14 days of treatment,and occurrence of adverse reactions during the treatment period were compared between the two groups.Results:After 14 days of treatment,the total effective rate in the study group was 93.75％,which was significantly higher than 80.00％of the control group(P＜0.05).Compared with before treatment,after 14 days of treatment,the Kofoed ankle joint function score increased in both groups,with a higher score in the study group(P＜0.05).The visual analog scale(VAS)scores,ankle joint circumference,interleukin-6,and high-sensitivity C-reactive protein levels decreased in both groups,with a lower level in the study group(P＜0.05).During the treatment period,the incidence of adverse reactions in the study group and the control group was 9.38％and 6.67％,respectively,with no significant difference(P＞0.05).Conclusion:Oral and external application of Modified Shaoyao Gancao Decoction has significant efficacy in the treatment of acute ankle sprain,which can alleviate ankle joint pain and swelling,improve ankle joint function,and reduce the level of serum inflammatory factors in patients with good safety.
Acute ankle sprainModified Shaoyao Gancao DecoctionOralExternal applicationAnkle joint function
NETL
NSTL
万方数据
维普
