首页|"致中和"理论指导下柴金利胆汤治疗肝癌急性肝功能衰竭的临床应用

"致中和"理论指导下柴金利胆汤治疗肝癌急性肝功能衰竭的临床应用

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急性肝功能衰竭是中晚期肝癌严重的并发症之一,系由多种原因引起的急性肝细胞大量坏死,或肝细胞出现严重功能障碍,致短期内进展至极度乏力、腹胀、肝性脑病、黄疸加深、凝血功能异常,甚至危及生命的一种危急重症,其发病迅速,病情凶险.中医学认为肝癌急性肝衰竭所属"急黄"范畴,病源在肝胆,多继发在其他疾病之后,瘀血阻滞,湿热残留,日久损肝伤脾.其病位主要在于肝胆脾胃,基本病机为脾胃虚弱,升降失司以致癌毒蕴积化毒,疫毒炽盛,搏结于肝胆.笔者认为在出现此类病症时,应以和为期,从"通腑"和"利湿"两方面分法辨证论治,提出应用柴金利胆汤治疗,以疏肝利胆通腑为先,以清热利胆退黄为要,并贯彻"致中和"的理论思想,抗癌的同时应祛邪与扶正相结合,同时注意疾病后的调治,临床效果甚佳.
Clinical Application of Chaijin Lidan Decoction in The Treatment of Acute Liver Failure of Liver Cancer under the Guidance of"Neutralization"
Acute liver failure is one of the serious complications of middle and advanced liver cancer,which is caused by a large number of acute hepatocyte necrosis or severe dysfunction of hepatocytes,resulting in short-term progression to hepatic encephalopathy and even life-threatening critical illness.Its disease is rapid and dan-gerous.According to traditional Chinese medicine,acute liver failure of liver cancer belongs to the category of"ful-minant jaundice",which is caused by liver and gallbladder,followed by other diseases,and blood stasis,residual dampness and heat all damage to the liver and spleen for a long time.The main location of the disease is the liver,gallbladder,spleen and stomach,and the basic pathogenesis is weakness of the spleen and stomach.The ascending and descending division accumulates the carcinogenic toxin,and the epidemic virus is blazing,fighting in the liver and gallbladder.The authors think that when this kind of disease occurs,it should be treated according to syn-drome differentiation from the two aspects of"dredging the Fu Organs"and"promoting dampness",and put for-ward the application of Chaijin Lidan Decoction,for soothing the liver and promoting gallbladder,clearing away heat and gallbladder and retreating jaundice,and carrying out the theoretical thought of"Neutralization".While fighting cancer,we should combine dispelling pathogens with supporting vital qi,and pay attention to the regula-tion and treatment after the disease.The clinical effect is excellent.

Liver cancerAcute Liver FailureNeutralizationFulminant jaundiceChaijin Lidan Decoction

庞雪莹、韩笑、张俐佳、宋爱英、刘业、张彤

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黑龙江中医药大学附属第一医院,黑龙江哈尔滨 150040

肝癌 急性肝衰竭 急黄 致中和 柴金利胆汤

中国博士后科学基金地区专项支持计划黑龙江省中医药管理局项目黑龙江省中医药管理局项目

2002MD713752ZHY2020-099ZHY18-059

2024

中国中医急症
中华中医药学会

中国中医急症

CSTPCD
影响因子:1.144
ISSN:1004-745X
年,卷(期):2024.33(2)
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