Effects of Xifeng Huatan Tongluo Granules on Lipid Metabolism,Hemorheology,and Neurological Func-tion in Patients with Acute Cerebral Infarction
Objective:To observe the effects of Xifeng Huatan Tongluo Granules on lipid metabolism,hemorhe-ology,and neurological function in patients with acute cerebral infarction.Methods:A total of 80 patients with acute cerebral infarction were selected and randomly divided into an observation group and a control group,with 40 cases each.The control group received routine treatment,while the observation group received treatment with Xifeng Huatan Tongluo Granules on the basis of the control group.The lipid metabolism indicators[total cholester-ol(TC),triglycerides(TAG),high-density lipoprotein cholesterol(HDLC),and low-density lipoprotein cholesterol(LDLC)],blood rheology[whole blood high shear viscosity(HSV),platelet adhesion rate(PAdR),and hematocrit(HCT)],cerebral blood perfusion[middle cerebral artery end-diastolic blood velocity(EDV),peak systolic flow velocity(PSV),and mean blood flow velocity(Vm)],National Institutes of Health Stroke Scale(NIHSS)scores and other levels of the two groups were recorded and compared.Results:After treatment,the levels of TC,TAG,HDLC,and LDLC in both groups improved compared with before treatment(P<0.05),and the observation group was significantly better than the control group(P<0.05);after treatment,the levelsof EDV,PSV and Vm in both group sincreased obvisouly(P<0.05),and the observation group washigher significantly than the controlgroup(P<0.05);after treatment,the levels of HSV,PAdR,and HCT in both groups decreased compared with before treatment(P<0.05),and the observation group was significantly lower than the control group(P<0.05);after treatment,the NIHSS scores of both groups decreased compared with before treatment(P<0.05),and the observation group was significantly lower than the control group(P<0.05).Conclusion:Xifeng Huatan Tongluo Granules can improve lipid metabolism,improve blood rheology,increase cerebral blood flow perfusion,and promote neurological function recovery in patients with acute cerebral infarction.
Acute cerebral infarctXifeng Huatan Tongluo GranulesLipid metabolismHemorheologyBrain perfusionNeurological function