Clinical Efficacy of Qingjin Huatan Decoction Combined with Conventional Western Medicine in Patients with AECOPD:a Meta-analysis
Objective:To investigate the effect of Qingjin Huatan Decoction combined with conventional west-ern medicine on the clinical efficacy of acute exacerbations of chronic obstructive pulmonary disease(AECOPD)patients by meta-analysis.Methods:Databases of CNKI,VIP,CBM,Wanfang,PubMed and The Cochrane Library were searched from inception to August 31,2023 for randomized controlled studies on the clinical efficacy of Qin-gjin Huatan Decoction combined with conventional western medicine in patients with AECOPD.Meta analysis of the extracted data was performed using Review Manger 5.3 software.Results:A total of 2 061 cases were includ-ed in 25 literatures,including 1 037 cases in the observation group and 1024 cases in the control group.Clinical efficacy of the observation group[MD=1.2,95％CI(1.15,1.25),P＜0.000 01],PO2[MD=4.43,95％CI(3.52,5.35),P＜0.01],FEV1[MD=0.27,95％CI(0.17,0.37),P＜0.01],FEV1/FVC％[MD=4.4,95％CI(3.46,5.34),P＜0.01]were higher than those in the control group,with statistical difference.The TCM syndrome scores of the ob-servation group[MD=-3.2,95％CI(-4.06,-2.34),P＜0.01],PCO2[MD=-5.93,95％CI(-7.11,-4.76),P＜0.01],WBC[MD=-0.7,95％CI(-1.05,-0.36),P＜0.01]were lower than the control group,with statistical difference.CRP in the observation group[MD=-2.11,95％CI(-4.57,0.36),P＜0.09]was lower than that in the control group,but there was no statistical difference.Conclusion:Qingjin Huatan Decoction combined with conventional western medicine can better improve the symptoms,pulmonary function and inflammatory indicators of patients with AECOPD.
NETL
NSTL
万方数据
