Clinical Efficacy of Dachengqi Decoction Combined with Intradermal Needling on Postoperative Ileus after Gastric and Duodenal Perforation Repair
Objective:To evaluate the efficacy of Dachengqi Decoction enema combined with intradermal nee-dling for postoperative ileus(POI)in patients after gastric and duodenal perforation repair,and its impact on in-flammatory factors and gastrointestinal hormones.Methods:A total of 60 patients with POI after gastric and duo-denal perforation repair were randomly divided into a control group(30 cases)and an observation group(30 cas-es).The control group received routine postoperative rehabilitation measures combined with intradermal needling,while the observation group was given Dachengqi Decoction enema on the basis of the control group for 3 days.The time of first anal discharge and defecation,recovery time of bowel sounds,and normal eating time,and evalu-ate the score of dampness heat stagnation syndrome before and after treatment,the postoperative gastrointestinal motility score,the disappearance time of abdominal distension,pain,nausea,and vomiting were recorded;the se-rum motilin(MTL),gastrin(GAS),vasoactive intestinal peptide(VIP),and tumor necrosis factor-αt(TNF-α),c-re-active protein(CRP),interleukin-1(IL-1),and IL-6 levels before and after treatment were detected and the safety evaluation was estimated.Results:After treatment,the observation group had shorter first exhaust and defecation times,recovery time of bowel sounds,normal eating time,and disappearance time of abdominal distension,abdomi-nal pain,nausea,and vomiting compared with the control group(P＜0.05);the score of dampness heat stagnation syndrome in the observation group was lower than that in the control group(P＜0.05),and the postoperative gastro-intestinal motility score was higher than that in the control group(P＜0.05);after treatment,the levels of TNF-α,CRP,IL-1,IL-6 and VIP in the observation group were lower than those in the control group(P＜0.05),while the levels of MTL and GAS were higher than those in the control group(P＜0.05);the total effective rate of clinical ef-ficacy in the observation group was 93.33％,which was higher than 63.33％in the control group(P＜0.05).Con-clusion:The combination of Dachengqi Decoction enema and intradermal needling for POI after gastric and duode-nal perforation repair can regulate gastrointestinal hormones,inhibit excessive intestinal inflammatory reactions,promote the recovery of gastrointestinal motility,accelerate the disappearance of symptoms and signs,shorten the course of the disease,improve clinical treatment effectiveness and promote postoperative recovery of patients.
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