首页|普通登革热中医证型之间实验室指标差异性的回顾性分析

普通登革热中医证型之间实验室指标差异性的回顾性分析

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目的 比较普通登革热不同中医证型的实验室指标,从而更好地指导临床中医辨证.方法 选取2014年至2020年于广州中医药大学第一附属医院住院的普通登革热患者,分析风热夹湿,邪在卫气证及湿热伤络,邪侵营血证这两个关键证型之间的白细胞计数、血小板计数、天门冬氨酸氨基转移酶、丙氨酸氨基转移酶、乳酸脱氢酶等实验室指标的差异性,统计分析采用SPSS21软件执行.结果 两组间基线一致,而血小板计数在湿热伤络,邪侵营血证中显著低于风热夹湿,邪在卫气证(P＜0.05);白细胞计数、天门冬氨酸氨基转移酶、丙氨酸氨基转移酶、乳酸脱氢酶、α-羟丁酸脱氢酶在湿热伤络,邪侵营血证中高于风热夹湿,邪在卫气证(P＜0.05);钠、渗透压、肌酸激酶同工酶水平虽在两证型之间存在差异(P＜0.05),但其水平均在正常范围内.余指标在两证型之间的差异无统计学意义.结论 普通登革热患者湿热伤络,邪侵营血证的实验室指标比风热夹湿,邪在卫气证的实验室指标更加严重,实验室指标变化符合中医证型规律,临床辨治普通登革热可参考实验室指标.
Exploration of the Differences in Laboratory Indicators between Traditional Chinese Medicine Syndrome Types of Dengue Fever Based on Retrospective Analysis
Objective:To compare the laboratory indicators of different Traditional Chinese Medicine(TCM)syndrome types of dengue fever,for guiding clinical TCM syndrome differentiation better.Methods:Patients with dengue fever admitted to the First Affiliated Hospital of Guangzhou University of Chinese Medicine from 2014 to 2020 were selected to analyze the differences in laboratory indicators such as white blood cell count,platelet count,aspartate aminotransferase,alanine aminotransferase,and lactic dehydrogenase between the two key TCM syndrome types:wind heat containing dampness and evil in the Weiqi syndrome and dampness heat damaging col-laterals and evil invading blood syndrome.Statistical analyses were performed using SPSS 21 software.Results:The baseline was consistent between two groups,and the platelet count in the syndrome of dampness heat damag-ing collaterals and evil invading blood was significantly lower than that in the syndrome of wind heat containing dampness and evil in the Weiqi(P＜0.05);white blood cell count,aspartate aminotransferase,alanine aminotrans-ferase,lactic dehydrogenase and α-hydroxybutyrate dehydrogenase were higher in the syndrome of dampness heat damaging collaterals and evil invading blood than in the syndrome of wind heat containing dampness and evil in the Weiqi(P＜0.05);although there were differences in the levels of sodium,osmotic pressure and creatine kinase isoenzymes between two TCM syndrome types(P＜0.05),their levels were all within the normal range.There was no statistically significant difference in the remaining indicators between two TCM syndrome types.Conclusion:The laboratory indicators of dampness heat damaging collaterals and evil invading blood syndrome are more seri-ous than those of wind heat containing dampness and evil in the Weiqi syndrome.Changes in laboratory indicators are consistent with changes in TCM syndrome types.Clinical diagnosis and treatment of dengue fever could refer to laboratory indicators.

Dengue feverTCM syndrome typeLaboratory indicatorsRetrospective study

谢铱子、蔡贝贝、詹少锋、江勇、刘小虹、温武金

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广东省深圳市中西医结合医院,广东深圳 518104

广州中医药大学,广东 广州 510405

广州中医药大学第一附属医院,广东广州 510405

广州中医药大学岭南医学研究中心,广东广州 510405

广东省中医临床研究院,广东广州 510405

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普通登革热 中医证型 实验室指标 回顾性研究

国家自然科学基金面上项目广东省重点领域研发计划深圳市"医疗卫生三名工程"建设项目深圳市"医疗卫生三名工程"建设项目深圳市宝安区医疗卫生科研项目广东省重点科室(中西医协同科室)建设项目

822744182020B1111100002SZZYSM202206013SZZYSM2021060062023JD107

2024

10.3969/j.issn.1004-745X.2024.05.006

中国中医急症
中华中医药学会

中国中医急症

CSTPCD
影响因子：1.144
ISSN：1004-745X
年,卷(期)：2024.33(5)
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