Xuanfu serves as the fundamental structural basis for the ascending,descending,entering,and exiting movements of essential substances in human physiological activities.It plays a pivotal role in the microcirculation within the brain.The brain is regarded as the abode of the primordial spirit,governing the spirits of all five organs;thus,the proper opening and closing functions of the cerebral Xuanfu are crucial prerequisites for the unobstructed circulation of Qi,blood,body fluids,and essence within the brain,forming the very foundation for the normal physi-ological functioning of the brain,particularly in its microcirculatory context.Migraine,whose location is attributed to the brain in TCM,is closely related to the cerebral Xuanfu.Therefore,the authors propose to commence from the perspective of"Opening Xuanfu"and first elucidate the theoretical connotations of this concept.Subsequently,the authors aim to apply this theory to analyze the pathogenesis and treatment of migraines,ultimately providing a reference for clinical practice and therapeutic strategies.
MigraineCerebral XuanfuBlood-brain barrierOpening XuanfuFeng drug
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