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穴位埋线治疗急性期带状疱疹临床观察

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目的 观察穴位埋线治疗急性期带状疱疹的疗效及对白细胞介素-1β(IL-1β)、白细胞介素-2(IL-2)、白细胞介素-6(IL-6)表达程度的影响.方法 选取68例患者依照随机数字表法分为两组各34例.两组均予西医常规基础药物口服,选择局部阿是穴,双侧合谷、曲池、太冲、阳陵泉、皮损对应神经节段夹脊穴.对照组予普通针刺处理,每天1次,治疗2周;治疗组予穴位埋线处理,每周1次,治疗2周.对比两组患者临床疗效,治疗前与治疗3、7、14d后视觉模拟评分量表(VAS)评分,治疗前后血清IL-1β、IL-2、IL-6水平,不良反应发生率.结果 两组总有效率相当(P>0.05),但治疗组显愈率为73.53%,高于对照组的44.12%(P<0.05);治疗3、7、14d后,治疗组VAS分值较对照组明显降低(P<0.05);治疗后两组患者IL-2水平均较治疗前有所升高(P<0.05),IL-1 β、IL-6水平均较治疗前下降(P<0.05),且治疗组数值变化幅度较对照组明显(P<0.05);治疗组总不良反应发生率低于对照组(P<0.05).结论 穴位埋线可尽快缓解带状疱疹患者急性期疼痛程度,减轻炎症反应水平,患者不良反应发生率低.
Clinical Observation of Acupoint Thread Embedding Therapy on Acute Herpes Zoster
Objective:To evaluate the therapeutic effect of acupoint thread embedding in the treatment of acute herpes zoster and its effect on the expression of interleukin-1 β(IL-1β),IL-2 and IL-6.Methods:A total of 68 patients were selected and randomly divided into an control group of 34 cases and a treatment group of 34 cases each,using a random number table method.Both groups were treated with conventional western medicine basic drugs orally,and local Ashi acupoints,bilateral Hegu,Quchi,Taichong,Yanglingquan,and corresponding nerve seg-ment Jiaji acupoints were selected.The control group was treated with regular acupuncture once a day for 2 weeks;the treatment group was treated with acupoint thread embedding once a week for 2 weeks.The clinical efficacy of two groups of patients,changes in Visual Analog Scale(VAS)scores before and after treatment for 3,7,14 d,hu-man serum differences in IL-1β,IL-2 and IL-6 levels before and after treatment,the incidence of adverse reac-tions were compared.Results:The total effective rate in the two groups was similar(P>0.05),but the proportion of total effective population(cured+significantly improved)in the treatment group was 73.53%,which was higher than that in the control group(44.12%)(P<0.05).After treatment for 3,7,and 14 d,the VAS score of the buried thread group was significantly lower than that of the control group(P<0.05).After treatment,the expression levels of IL-2 in both groups of patients increased compared with before treatment(P<0.05);IL-1β and IL-6 decreased compared with before treatment(P<0.05),and the numerical changes in the treatment group were more significant than those in the control group(P<0.05).The overall incidence of adverse reactions in the treatment group was lower than that in the control group(P<0.05).Conclusion:Acupoint thread embedding can quickly alleviate the acute pain level of herpes zoster patients,reduce the level of inflammatory response,and have a low incidence of adverse reactions.

Herpes zosterPostherpetic neuralgiaAcupoint thread embeddingInterleukin-1βInterleukin-2Interleukin-6

邵翠丽、王悦、徐炳国、张加英

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南京医科大学附属南京医院,江苏省南京市第一医院,江苏南京 210006

带状疱疹 带状疱疹后遗神经痛 穴位埋线 白细胞介素-1β白细胞介素-2白细胞介素-6

江苏省中医药科技发展计划

YB2020005

2024

中国中医急症
中华中医药学会

中国中医急症

CSTPCD
影响因子:1.144
ISSN:1004-745X
年,卷(期):2024.33(5)
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