Effect of Cixue Xingnao Method on Cerebral Hemodynamics in Patients with Acute Cerebral Infarction
Objective:To observe the effects of Cixue Xingnao Method on cerebral hemodynamics and serum VEGF and bFGF in patients with acute cerebral infarction,to investigate the clinical value and possible mecha-nism of this protocol.Methods:A total of 62 patients with acute cerebral infarction were selected and divided in-to 31 patients each in the treatment group and control group according to the random number table method.The control group was given standardized western medical treatment combined with rehabilitation therapy,and the treat-ment group was given Cixue Xingnao Method on the basis of the control group.The acupuncture points were Shixu-an,Yongquan,Shaochonig and Baihui acupoints on the affected side once a day for 14 days.During the study peri-od,changes in NIHSS and Barthel scores,changes in serum VEGF and bFGF values in patients with acute cere-bral infarction before and after treatment were recorded,and cerebral hemodynamics before and after treatment were recorded using transcranial Doppler ultrasound(TCD).Results:The NIHSS score decreased in both groups after treatment compared with that before treatment(P＜0.05),and the decrease was more significant in the treat-ment group than in the control group(P＜0.05);the Barthel score increased in both groups after treatment com-pared with that before treatment(P＜0.05),and the increase was more significant in the treatment group than in the control group(P＜0.05);Vd,Vs,and Vm of the middle cerebral artery on the side of the lesion were significant-ly faster in both groups after treatment than before treatment(P＜0.05),and the treatment group was significantly better than the control group(P＜0.05);PI and RI were significantly lower in both groups after treatment than be-fore treatment,but the degree of reduction was comparable in both groups(P＞0.05);VEGF and bFGF were signifi-cantly higher in both groups after treatment than before treatment(P＜0.05),and the treatment group was signifi-cantly better than the control group(P＜0.05).Conclusion:Cixue Xingnao Method can effectively improve neuro-logical impairment and living quality of ACI patients.Its mechanism might be relevant to the improvement of cere-bral blood circulation and vascular renewal.
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