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清瘿解毒方联合针刺治疗亚急性甲状腺炎引发疼痛的临床观察

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目的 观察清瘿解毒方联合针刺治疗亚急性甲状腺炎引发疼痛的临床疗效.方法 选择亚急性甲状腺炎疼痛患者84例,根据随机数字表法分为观察组与对照组各42例,对照组给予抗炎止痛常规治疗及针刺治疗,观察组在对照组基础上给予清瘿解毒方口服.观察两组治疗前后临床疗效、中医证候评分、血清疼痛因子[血清P物质(SP)、β-内啡肽(β-EP)、强啡肽(DYN)]水平、甲状腺功能指标[促甲状腺激素(TSH)、游离三碘甲状原氨酸(FT3)、游离甲状腺素(FT4)]、疼痛评分[视觉模拟疼痛评分(VAS),数字疼痛强度量表(NRS)]及安全性评价.结果 治疗后观察组总有效率为92.86%,显著高于对照组的76.19%(P<0.05);两组中医证候评分、SP、β-EP、DYN水平及VAS、NRS评分均较治疗前降低,且观察组低于对照组(P<0.05);两组TSH水平显著高于治疗前,FT3、FT4水平显著低于治疗前,且观察组优于对照组(P<0.05).两组治疗过程未出现不良事件.结论 清瘿解毒方联合针刺治疗亚急性甲状腺炎引发疼痛临床疗效显著.
Clinical Observation on the Treatment of Pain caused by Subacute Thyroiditis with Qingying Jiedu Decoction combined with Acupuncture
Objective:To investigate the clinical effect of Qingying Jiedu Decoction combined with acupuncture in the treatment of pain caused by subacute thyroiditis.Methods:A total of 84 cases of subacute thyroiditis pain patients were divided into the observation group and the control group according to random number table method;the control group was given anti-inflammation and analgesic conventional treatment and acupuncture treatment,while the observation group was given Qingying Jiedu Decoction on the basis of the control group.The clinical effi-cacy,TCM syndrome score,serum pain factors[serum substance P(SP),β-endorphin(β-EP),strong enkephalin(DYN)]levels,thyroid function indicators[thyroid-stimulating hormone(TSH),free thyroxine3(FT3),free thyrox-ine4(FT4)],pain scores[visual analogue scale(VAS),numerical rating scale(NRS)]and safety evaluation before and after treatment were observed in the two groups.Results:After treatment,the total effective rate in the obser-vation group was 92.86%,which was higher than 76.19%in the control group(P<0.05).TCM syndrome score,se-rum pain factors and pain scores of the two groups were decreased after treatment(P<0.05).TSH levels of the two groups were significantly higher than before treatment,and FT3 and FT4 levels of the two groups were signifi-cantly lower than before treatment.All of the indicators in the observation group were better than those in the con-trol group(P<0.05).There were no adverse events during treatment in the two groups.Conclusion:Qingying Jie-du Decoction combined with acupuncture has significant clinical effect on pain caused by subacute thyroiditis.

Subacute thyroiditisQingying Jiedu DecoctionAcupuncturePain factorPain score

杜亮亮、曾豆云、贺大智、戴北方

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湖南省岳阳市中医医院,湖南岳阳 414000

亚急性甲状腺炎 清瘿解毒方 针刺 疼痛因子 疼痛评分

湖南省卫生健康委科研立项项目

20201374

2024

中国中医急症
中华中医药学会

中国中医急症

CSTPCD
影响因子:1.144
ISSN:1004-745X
年,卷(期):2024.33(5)
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