Efficacy Observation of Sheshang Decoction Combined with External Application of Sheshang Ointment in the Treatment of Pallas Pit Viper Bite
Objective:To observe the effect of Sheshang Decoction combined with external application of Sheshang Ointment after Pallas pit viper bite(fire-toxicity syndrome).Methods:60 patients with Pallas pit viper bite(fire-toxicity syndrome)were selected and randomly divided into the control group and the treatment group,with 30 cases in each group.The patients in the control group received conventional western medicine treatment combined with traditional Chinese medicine acupuncture and cupping.On the basis of the control group's treat-ment,the patients in the treatment group were treated with Sheshang Decoction combined with external application of Sheshang Ointment.The changes in inflammatory indicators such as serum white blood cells,neutrophils,and hypersensitive C-reactive protein(hs-CRP),as well as myocardial enzyme spectrum indicators such as lactate de-hydrogenase(LDH),creatine kinase(CK),and creatine kinase isoenzyme(CK-MB)before and after treatment in both groups of patients were observed.Results:The serum levels of white blood cells,neutrophils,hs-CRP,LDH,CK,and CK-MB in both groups of patients decreased significantly compared to before treatment.Compared with the control group,the treatment group showed a more significant decrease in inflammatory indicators and myocardi-al enzymes(P＜0.05).Conclusion:Sheshang Decoction for oral administration combined with external application of Sheshang Ointment can effectively reduce the systemic inflammatory response of patients and alleviate the dam-age of Pallas pit viper venom to human myocardial cells.
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