首页|独活桂辛方对腰椎间盘突出症(肝肾亏虚证)患者疼痛及腰椎功能的影响

独活桂辛方对腰椎间盘突出症(肝肾亏虚证)患者疼痛及腰椎功能的影响

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目的 观察独活桂辛方联合针刺、布洛芬缓释胶囊治疗腰椎间盘突出症(肝肾亏虚证)的临床疗效.方法 将85例患者随机分为两组,观察组43例,予以独活桂辛方联合针刺、布洛芬缓释胶囊口服,对照组42例,予以针刺联合布洛芬缓释胶囊口服.疗程3周.结果 观察组总有效率为92.68%,高于对照组的78.05%(P<0.05).治疗后及随访时,两组患者中医症状积分、视觉模拟量表(VAS)评分、Roland-Morris功能障碍调查表(RMDQ)均较治疗前明显降低(P<0.05),观察组下降更明显(P<0.05);两组患者日本骨科协会腰椎(JOA)评分均较治疗前明显升高(P<0.05),观察组升高更明显(P<0.05).治疗后,两组患者血清白细胞介素-1β(IL-lβ)、白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)水平均较治疗前明显下降,观察组下降更明显(P<0.05).结论 独活桂辛方联合针刺、布洛芬缓释胶囊可减轻腰椎间盘突出症(肝肾亏虚证)患者腰腿疼痛症状,降低血清IL-1β、IL-6、h-CRP水平,改善腰椎功能.
The Effect of Duhuo Guixin Decoction on Pain and Lumbar Function in Lumbar Disc Herniation with Liver-kidney Deficiency Pattern
Objective:To observe the curative effect of Duhuo Guixin Decoction combined with acupuncture and ibuprofen sustained-release capsule in the treatment of lumbar disc herniation with liver and kidney deficiency pattern.Methods:Totally 85 patients with lumbar disc herniation of liver and kidney deficiency pattern were ran-domly divided into two groups according to the time sequence of enrollment.The observation group with 43 cases was treated with Duhuo Guixin Decoction combined with acupuncture and ibuprofen sustained-release capsules.The control group with 42 cases was treated with acupuncture combined with ibuprofen sustained-release cap-sules.The treatment course was 3 weeks.Results:The total effective rate was 92.68%in the observation group,which was higher than 78.05%in the control group(P<0.05).After treatment and during the follow-up,the scores of TCM symptoms,VAS and RMDQ in the two groups were significantly lower than those before treatment(P<0.05),and the decrease in the observation group was more significant(P<0.05).The JOA scores of lumbar spine in the two groups were significantly higher than those before treatment(P<0.05),and the increase in the ob-servation group was more significant(P<0.05).After treatment,the levels of serum inflammatory factors IL-1β,IL-6 and h-CRP in the two groups were significantly lower than those before treatment,and the decrease in the observation group was more significant(P<0.05).Conclusion:Duhuo Guixin Decoction combined with acupunc-ture and ibuprofen sustained-release capsule can alleviate the symptoms of lumbocrural pain in patients with lum-bar disc herniation of liver and kidney deficiency pattern,reduce the levels of serum IL-lβ,IL-6 and h-CRP,and improve lumbar function,and the clinical application is safe and effective.

Lumbar disc herniationDuhuo Guixin DecoctionLiver and kidney deficiency patternPainLum-bar function

王冠军、毕俊芳、张素娟、刘欣、解纪惠、张意侗、李承骏

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河北省石家庄市中医院,河北石家庄 050051

腰椎间盘突出症 独活桂辛方 肝肾亏虚型 疼痛 腰椎功能

河北省中医药局科研项目

2019447

2024

中国中医急症
中华中医药学会

中国中医急症

CSTPCD
影响因子:1.144
ISSN:1004-745X
年,卷(期):2024.33(6)
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