Effect of Jiegu Ointment on Rib Fracture Combined with Pulmonary Contusion and Its Impact on Pain Factors and Inflammatory Factors
Objective:To explore the clinical effect of using Jiegu Ointment in treatment of rib fractures com-bined with pulmonary contusion,and its impact on pain factors and inflammatory factors.Methods:A total of 98 patients with rib fractures and pulmonary contusions were randomly divided into control group and observation group,and 49 cases were in each group.The control group was given routine treatment,while the observation group received external application of Jiegu Ointment on the basis of the control group.The pain VAS scores,sim-ple scores of lung contusion,scores qi stagnation and blood stasis syndrome were recorded;the blood gas analysis indicators,chest tube retention time,first time out of bed activity time,hospitalization time,the occurrence of com-plications and the clinical efficacy of two groups were compared;the inflammatory and pain factors were detected.Results:After 3,5,and 7 days of treatment,the VAS scores of both groups significantly decreased(P＜0.05),and the VAS scores at each time point were lower than those of the control group during the same period(P＜0.05);af-ter treatment,the simplified score of lung contusion and the integral of qi stagnation and blood stasis syndrome de-creased in both groups(P＜0.05),and the observation group was lower than the control group(P＜0.05);after treat-ment,PaO2 and oxygenation index increased(P＜0.05)and PaCO2 decreased(P＜0.05)in both groups.The obser-vation group had higher PaO2 and oxygenation index than the control group(P＜0.05),and the PaCO2 level was low-er than the control group(P＜0.05);after treatment,the observation group had shorter chest tube retention time,first time out of bed activity time,and hospitalization time than the control group(P＜0.05);after treatment,the in-flammatory factors CRP,TNF-α and IL-6 in both groups significantly decreased(P＜0.05),and the observation group was lower than the control group(P＜0.05);after treatment,the levels of pain inducing factors PGE2,5-HT,and SP in both groups significantly decreased(P＜0.05),and the index in the observation group was lower than the control group(P＜0.05);the incidence of complications in the observation group was lower than the control group(P＜0.05);the total effective rate of the observation group was higher than the control group(P＜0.05).Con-clusion:The clinical efficacy of Jiegu Ointment in the treatment of early patients with rib fractures and pulmonary contusions is significant.In the early stage,it can minimize patient pain,shorten the course of the disease,reduce complications,improve lung function,and promote the recovery of fractures and pulmonary contusions.
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