Clinical Study on the Treatment of Abnormal Coagulation Function Caused by Venomous Snake Bite with Traditional Chinese Medicine of Promoting Coagulation Formula
Objective:To explore the therapeutic effect of traditional Chinese medicine Promoting Coagulation Formula on coagulation dysfunction caused by venomous snake bites.Methods:A total of 116 patients with ven-omous snake bites admitted were selected as the study subjects,and they were randomized into a conventional group(58 cases)and a combined group(58 cases)using a random number table method.After admission,both groups were given routine treatment,while the combined group was given Promoting Coagulation Formula.The swelling degree,coagulation function indicators,blood routine indicators,and hospitalization time between the two groups before treatment,1st day of treatment,3rd day of treatment,6th day of treatment were compared.Results:There was 1 case of drop-out in the conventional group and 4 cases of drop-out in the combined group.The de-gree of swelling in both groups improved on the 3rd and 6th day of treatment,and the distribution of swelling lev-els in the combined group were better than those in the conventional group on the 3rd and 6th day of treatment(P＜0.05).The combined group had shorter prothrombin time on the 1st day of treatment,as well as shorter pro-thrombin time,activated partial thromboplastin time,and thrombin time on the 3rd and 6th days of treatment com-pared with the conventional group.The fibrinogen level on the 6th day of treatment was higher than that of the con-ventional group(P＜0.05).The red blood cell count,hemoglobin on the 3rd day of treatment,and platelet count on the 6th day of treatment in the combined group were higher than those in the conventional group(P＜0.05).The hospitalization time in the combined group was shorter than that in the conventional group(P＜0.05)].Conclu-sion:On the basis of routine treatment for patients with abnormal coagulation function caused by venomous snake bites,the combination with Promoting Coagulation Formula can promote swelling relief,improve coagulation func-tion,and shorten hospitalization time.
Venomous snake bitesCoagulation functionTraditional Chinese medicinePromoting Coagulation Formula
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