Clinical Observation on Shangke Huangshui Medicated Gauze Combined with Guyi Decoction in Preventing the Incidence of DVT in Early Femoral Intertrochanteric Fracture
Objective:To observe the clinical effect of Shangke Huangshui Medicated Gauze combined with Guyi Decoction for preventing deep vein thrombosis(DVT)in early femoral intertrochanteric fracture(FIF)patients based on the concept of enhanced recovery after surgery(ERAS).Methods:A total of 120 FIF patients were ran-domly divided into two groups,with 60 cases in each group.The control group was treated with a conventional ERAS regimen.On the basis of the control group,the treatment group was given Shangke Huangshui Medicated Gauze for external application combined with Guyi Decoction for oral administration.Serum D-dimer(D-D),hemo-globin(HGB),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),and hemorheological(ηbrH,ηbrL,ηp)levels were examined in both groups on day 1,3 and 7,while the lower limb blood vessel ultrasonography was measured on day 2 and 7.Results:The differences between baseline data and day 1's D-D,HGB,ESR,CRP,ηbrH,ηbrL,and ηp levels were not statistically significant(P＞0.05).The contents of D-D,ESR,CRP,ηbrH,ηbrL,and ηp in both groups showed a tendency to increase and then decrease with time(P＜0.05).On days 3 and 7,the treatment group was less than the control group,and the differences were all statistically significant(P＜0.05).The incidence of DVT in the treatment group(2 cases,3.33％)was less than that in the control group(8 cases,13.33％)(P＜0.05).Conclusion:Based on the concept of ERAS,the Shangke Huangshui Medicated Gauze combined with Guyi Decoction can reduce inflammatory response,decrease coagulation and fibrinolytic activity,im-prove blood stasis,and reduce the incidence of DVT in patients with FIF.
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