Efficacy of Modified Shengyang Yiwei Decoction in the Treatment of Eczema with Syndrome of Excessive Dampness-heat
Objective:To observe the efficacy of Modified Shengyang Yiwei Decoction in the treatment of ecze-ma with syndrome of excessive dampness-heat.Methods:A total of 98 patients were randomly divided into the control group and observation group(49 cases in each group).The control group was lightly coated with compound flamethasone ointment.The conventional western medicine in the observation group was the same as that in the control group,and Modified Shengyang Yiwei Decoction was added for treatment.The two groups were observed continuously for 2 weeks.The therapeutic effect,eczema area and severity index(EASI)score,visual analog scale(VAS)score,syndrome of excessive dampness-heat score,and serum tumor necrosis factor(TNF)-a,interleukin(IL)-4,1L-6 levels were compared between the two groups.Results:The total effective rate of observation group was 83.67％,which was significantly higher than 67.35％of control group(P＜0.05).After 2 weeks of treatment,the EASI and VAS scores were significantly reduced in two groups and reduced more significantly in observation group(P＜0.05).After 1 week and 2 weeks of treatment,the syndrome of excessive dampness-heat score in the two groups was significantly reduced,and the simultaneous point in the observation group was more significantly decreased after treatment(P＜0.05).After 2 weeks of treatment,serum levels of TNF-α,IL-4 and IL-6 in two groups were significantly reduced,and the reduction was more significant in observation group(P＜0.05).Conclu-sion:Modified Shengyang Yiwei Decoction in the treatment of eczema with syndrome of excessive damp-heat has an evident effect,can effectively control the condition,relieve itching,improve traditional Chinese medicine syn-dromes,and inhibit inflammation.
EczemaShengyang Yiwei DecoctionSyndrome of excessive dumpness-heatTumor necrosis factor-alphaInterleukin-4Interleukin-6
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