Study on Microscopic Syndrome Differentiation Characteristics of Toxin-heat Obstructing Lung Syndrome in Children with Severe Mycoplasma Pneumonia Based on Collateral Disease Theory
Objective:To classify the microscopic manifestations of severe mycoplasma pneumoniae pneumonia(SMPP)with toxic-heat obstructing lung syndrome in children into"lung collateral phlegm obstruction syndrome"and"lung collateral phlegm stasis syndrome"using fiberoptic bronchoscopy technology and based on the theory of collaterals.Combined with modern laboratory detection technology and methods,the clinical differences between the two groups are compared to enrich the basis for SMPP diagnosis and improving clinical efficacy.Methods:A total of 206 children with SMPP who underwent fiberoptic bronchoscopy in the Department of Traditional Chinese Medicine at Beijing Children's Hospital were collected.Based on the diagnostic criteria of Chinese and western medicine,combined with the theory of collaterals and the microscopic manifestations under fiberoptic bronchosco-py,children with SMPP with toxic-heat obstructing lung syndrome were divided into"lung collateral phlegm ob-struction syndrome"and"lung collateral phlegm stasis syndrome".The general information and laboratory indica-tors of the children were recorded and the differences between the two groups were compared,and the significance of the two groups of diagnostic typing was discussed from the perspectives of Chinese and western medicine.Results:In the lung collateral phlegm stasis syndrome,CRP,SF,ALT,AST,D-D,and FIB were higher than in the lung collateral phlegm obstruction syndrome(P<0.05),and PLT,ALB were lower than in the lung collateral phlegm obstruction syndrome(P<0.05);the rest of the differences were not statistically significant(P>0.05).Con-clusion:In the microscopic diagnostic typing of SMPP with toxic heat and lung closure,the toxic-heat in the lung collateral phlegm stasis syndrome is more severe,the damage to the body fluid and the consumption of Qi are more obvious,and the obstruction of blood stasis is more obvious,which is more likely to lead to changes.There-fore,in future treatment,toxic-heat obstructing lung syndrome may need to be treated on the basis of routine diag-nostic treatment,combined with bronchoscopy results,strengthening the treatment of removing blood stasis,dredg-ing the liver and discharging heat,benefiting Qi and supporting the body's resistance,in order to promote clinical recovery.
Severe mycoplasma pneumoniae pneumonia in childrenCollateral disease theoryToxin-heat ob-structing lung syndromeMicroscopic syndrome differentiation