Clinical Observation of Maotao Erchen Decoction in Treating Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Objective:To observe the clinical efficacy of Maotao Erchen Decoction in treating patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and its effects on inflammatory markers and arterial blood gas analysis.Methods:60 AECOPD patients were randomly divided into a conventional group and a Maotao group,each consisting of 30 cases.The conventional group received standard western medical treat-ments including oxygen therapy,bronchodilators,and anti-inflammatory drugs according to their condition.The Maotao group received the same standard western medical treatments combined with oral administration of Maotao Erchen Decoction.Both groups were treated for two weeks,after which the clinical efficacy,traditional Chinese med-icine symptom scores,inflammatory markers,and arterial blood gas analysis results were evaluated.Results:After treatment,the overall effective rate was 90.00%in the Maotao group,which was significantly higher than 76.67%in the conventional group(P<0.05).After treatment,both groups showed significant reductions in cough,sputum production,dyspnea,chest tightness,fatigue scores,and total scores compared with before treatment levels(P<0.01),with the Maotao group demonstrating significantly lower scores for cough,sputum production,chest tight-ness,and fatigue compared with the conventional group(P<0.05).Serum levels of C-reactive protein(CRP),pro-calcitonin(PCT),and interleukin-6(IL-6)decreased significantly after treatment in both groups(P<0.01),with the Maotao group showing more significant reductions in CRP,PCT,and IL-6 levels compared with the convention-al group(P<0.05).After treatment,both groups showed significant improvements in arterial blood gas analysis pa-rameters,including partial pressure of oxygen(PaO2)and carbon dioxide(PaCO2),with the Maotao group showing more significant improvements compared with the conventional group(P<0.05).Conclusion:The combination of Maotao Erchen Decoction with standard western medical therapy effectively improves clinical symptoms in AECO-PD patients,reduces inflammation markers,improves arterial blood gas analysis parameters,and enhances clinical efficacy.
Acute exacerbation of chronic obstructive pulmonary disease(AECOPD)Radix fici hirtaeErchen DecoctionMaotao Erchen DecoctionInflammatory markersArterial blood gas analysis