Clinical Study on Changfeng Decoction Internal Drink and Enema for Acute Radiation Proctitis after Cervical Cancer Radiotherapy
Objective:To observe the clinical efficacy of Changfeng Decoction enema in treating acute radiation proctitis(ARP)after cervical cancer radiotherapy.Methods:Ninety ARP patients after cervical cancer radiothera-py were randomly allocated into a control group(45 cases)receiving western medicine enemas and an observation group(45 cases)receiving Changfeng Decoction internal drink and enema.Clinical efficacy,pre-and post-treat-ment scores of TCM syndromes,rectal mucosa condition,Karnofsky performance status(KPS)scores,levels of in-flammatory factors,and incidence of adverse reactions were compared between the two groups.Results:The over-all effective rate in the observation group was 93.33％,which was significantly higher than 73.33％in the control group(P＜0.05).After treatment,the observation group demonstrated significantly improved TCM syndrome scores,rectal mucosa scores,inflammatory factor levels,and KPS scores compared with the control group(P＜0.05).Con-clusion:Internal drink and enema of Changfeng Decoction enhances quality of life and contributes to suppressing the expression of inflammatory cytokines.
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