Clinical Observation of Shenmai Injection as an Adjuvant Therapy for Severe Acute Pancreatitis
Objective:To observe the clinical efficacy of Shenmai Injection in the adjuvant treatment of severe acute pancreatitis(SAP).Methods:SAP patients were randomly divided into a control group of 44 cases(2 cases dropped out,2 cases excluded,and finally 40 cases completed)and an observation group of 45 cases(1 case dropped out,3 cases excluded,and finally 41 cases completed)using a random number table method.The control group received routine medicine treatment,while the observation group received additional Shenmai Injection in ad-dition to routine medicine treatment.After one week of treatment,the changes in clinical symptoms,vital signs,and laboratory indicators between the two groups were compared.Results:The total effective rate of the observa-tion group was significantly higher than that of the control group(P＜0.05).The tolerance rate of enteral nutrition and the improvement rate of traditional Chinese medicine symptoms in the observation group were significantly higher than those in the control group(P＜0.05).The bedside score and APACHE Ⅱ score of two groups of pa-tients with acute pancreatitis decreased compared with before treatment(P＜0.05),and the observation group was better than the control group(P＜0.05).The serum levels of WBC,CRP,PCT,and IL-6 in both groups of cases de-creased compared to before treatment(P＜0.05),and the observation group was better than the control group(P＜0.05).In addition,no serious adverse reactions were observed during the treatment of both groups.Conclusion:Shenmai Injection as an adjuvant therapy for SAP can improve clinical symptoms,reduce the severity of the condi-tion,and improve clinical prognosis.
Severe acute pancreatitisInflammatory responseAcute deficiency syndromeShenmai Injection
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NSTL
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