Clinical Observation of Intestinal Conditioning Formula Enema as an Adjuvant Treatment for Severe Pneumonia with Gastrointestinal Dysfunction
Objective:To observe the clinical efficacy and safety of adding intestinal conditioning formula ene-ma to western medicine treatment in patients with severe pneumonia and gastrointestinal dysfunction(syndrome of excessive fu-viscera caused by phlegm-heat).Methods:A total of 60 patients with severe pneumonia and gastro-intestinal dysfunction(syndrome of excessive fu-viscera caused by phlegm-heat)were included in this study,divid-ed equally into a treatment group and a control group,30 patients each.Both groups received standard western medical basic treatment,while the treatment group additionally received intestinal conditioning formula retention enemas.Each enema was retained for 20 minutes,once daily for a total of 7 days.The inflammatory markers,gas-trointestinal function indicators,APACHE Ⅱ,CPIS,and GIDS scores of both groups were observed before treatment and 7 days after treatment to evaluate the clinical efficacy and safety of the intestinal conditioning formula in treat-ing severe pneumonia with gastrointestinal dysfunction(syndrome of excessive fu-viscera caused by phlegm-heat).Results:After treatment,there were statistically significant differences in the gastrointestinal function indicators(AC,IAP)and inflammatory markers(WBC,N％,CRP,PCT)of the treatment group compared with before treat-ment,and these were lower than those of the control group(P＜0.05).After treatment,the GIDS,APACHEII scores,and CPIS of the treatment group decreased,and were lower than those of the control group.Statistical analy-sis showed that the differences after treatment between the two groups were significant(P＜0.05).The efficacy of the treatment group(83.33％)was better than that of the control group(56.67％)(P＜0.05).Conclusion:Intesti-nal conditioning formula enema combined with standard western medical treatment for patients with severe pneu-monia and gastrointestinal dysfunction(syndrome of excessive fu-viscera caused by phlegm-heat)has shown promising results.
Severe pneumoniaGastrointestinal dysfunctionIntestinal conditioning formulaTCM enema
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