Clinical Observation of the Efficacy of the Jiedu Xiefei Mixture in Treating Elderly Patients with Severe Pneumonia(Syndrome of Phlegm-heat Obstructing Lung)
Objective:To observe the efficacy of the Jiedu Xiefei mixture in treating elderly patients with severe pneumonia(syndrome of phlegm-heat obstructing lung)and to explore its mechanism of action.Methods:60 pa-tients were randomly divided into a control group and an observation group of 30 patients each using the random number table method.The control group received routine western medical treatment,while the observation group re-ceived Jiedu Xiefei mixture via nasogastric tube in addition to western medical treatment.The treatment duration was 14 days.The therapeutic effects of both groups were compared.Results:After treatment,the overall TCM ef-fective rate in the observation group was 80.00%,which was higher than 63.33%in the control group(P<0.05).Additionally,the observation group showed a more significant decrease in C-reactive protein(CRP),white blood cell count(WBC),and interleukin-6(IL-6)levels(P<0.05),and more remarkable improvements in the Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ)score and Clinical Pulmonary Infection Score(CPIS)(P<0.05)compared with the control group.Conclusion:Jiedu Xiefei mixture can alleviate inflammatory reac-tions and improve clinical symptoms,demonstrating significant efficacy in treating elderly patients with severe pneumonia(syndrome of phlegm-heat obstructing lung).
Severe pneumoniaJiedu xiefei mixturePhlegm-heat obstructing lungClinical observation