Clinical Observation of Acupuncture Combined with Modified Jiechuan Decoction in Treating Acute Ischemic Stroke-associated Pneumonia(Syndrome of Phlegm-heat Obstructing Lung)
Objective:To observe the application value of acupuncture combined with modified Jiechuan Decoc-tion in treating acute ischemic stroke(AIS)-associated pneumonia(syndrome of phlegm-heat obstructing lung).Methods:A total of 112 patients were randomly divided into four groups of 28 patients each using the random en-velope method:a conventional group(routine western medicine treatment),an acupuncture group(acupuncture treatment in addition to the conventional group's treatment),a TCM group(modified Jiechuan Decoction treatment in addition to the conventional group's treatment),and a combined group(acupuncture and modified Jiechuan De-coction treatment in addition to the conventional group's treatment).After four weeks of treatment,the efficacy,TCM syndrome scores,inflammatory factor levels,immune function,pathogen clearance rates,and adverse reaction incidences were compared among the groups.Results:The overall effective rate of the combined group(96.43％)was higher than that of the conventional group(67.86％),the TCM group(78.57％),and the acupuncture group(78.57％)(P＜0.05).There were no significant differences in the overall effective rates among the conventional,TCM,and acupuncture groups(P＞0.05).After treatment,the TCM syndrome scores,white blood cell counts(WBC),C-reactive protein(CRP),and interleukin-6(IL-6)levels were lower in the acupuncture,TCM,and com-bined groups than in the conventional group,while immunoglobulin M(IgM)and immunoglobulin G(IgG)levels were higher(P＜0.05).After treatment,the TCM syndrome scores,WBC,CRP,and IL-6 levels were lower in the combined group than in the acupuncture and TCM groups,while IgM and IgG levels were higher(P＜0.05).There were no significant differences in the TCM syndrome scores,WBC,CRP,IL-6,IgM,and IgG levels between the acupuncture and TCM groups(P＞0.05).The pathogen clearance rate in the combined group(46.43％)was higher than that in the conventional group(10.71％),the TCM group(21.43％),and the acupuncture group(21.43％)(P＜0.05).There were no significant differences in the pathogen clearance rates among the conventional,TCM,and acu-puncture groups(P＞0.05).The incidence of adverse reactions did not differ significantly among the groups(P＞0.05).Conclusion:Acupuncture combined with modified Jiechuan Decoction is effective in treating AIS-associat-ed pneumonia(syndrome of phlegm-heat obstructing lung),effectively improving clinical symptoms,achieving a high pathogen clearance rate,improving inflammatory factor levels and immune function,without increasing ad-verse reactions,and ensuring high safety.
Acute ischemic strokePneumoniaAcupunctureModified Jiechuan DecoctionSyndrome of phlegm-heat obstructing lungInflammatory factors
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