Observational Study of Modified Shixiao Qili Powder Combined with Low Molecular Weight Heparin Calcium in Preventing Deep Vein Thrombosis Formation after Total Hip Arthroplasty
Objective:To observe the efficacy of modified Shixiao Qili powder combined with low molecular weight heparin calcium in preventing deep vein thrombosis(DVT)formation after total hip arthroplasty(THA).Methods:A total of 90 elderly patients with femoral neck fractures undergoing THA were selected and randomly divided into three groups A,B,and C,with 30 patients in each group.Group A received modified Shixiao Qili pow-der acupoint patch combined with subcutaneous injection of low molecular weight heparin calcium.Group B re-ceived modified Shixiao Qili powder oral decoction combined with subcutaneous injection of low molecular weight heparin calcium.Group C received only subcutaneous injection of low molecular weight heparin calcium.The inci-dence of DVT,circumference of affected limbs,pain,plasma D-dimer levels,postoperative wound drainage volume,and local skin conditions were compared among the three groups.Results:The postoperative DVT incidence in Groups A and B was lower than in Group C,but the difference was not statistically significant(P＞0.05).After in-tervention,the difference in thigh and calf circumferences decreased in all three groups,with Group A showing bet-ter improvement than Groups B and C,although the difference was not statistically significant(P＞0.05).Plasma D-dimer levels gradually decreased after intervention,and the comparison among the three groups on postoperative day 1 and day 3 showed statistical significance(P＜0.05).The wound drainage volume within 48 hours postopera-tively was significantly lower in Group A compared with Groups B and C,with statistical significance(P＜0.05).Subcutaneous ecchymosis occurred in one case in both Groups A and B,and in three cases in Group C,with no significant difference(P＞0.05).Postoperative pain scores using the numerical rating scale showed statistical signif-icance(P＜0.05).Conclusion:Compared with monotherapy with low molecular weight heparin calcium,the combi-nation with modified Shixiao Qili powder in THA patients can reduce the incidence of DVT,alleviate skin ecchy-mosis,and decrease pain levels.The acupoint patch group showed better efficacy than the oral decoction group in reducing swelling in the affected limb and decreasing postoperative bleeding volume,with high safety.
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