Clinical Observation on the Treatment of Diarrhea-predominant Irritable Bowel Syndrome by Scraping and Detoxification Therapy of Zhuang Medicine
Objective:To observe the clinical efficacy of scraping and detoxification therapy of Zhuang medi-cine in the treatment of diarrhea-predominant irritable bowel syndrome(IBS-D)and its effect on serum pain medi-ators.Methods:60 patients with IBS-D were randomly divided into observation group and control group,with 30 cases in each group.The observation group was treated with scraping and detoxification therapy of Zhuang medi-cine,and the control group was treated with pinaverium bromide tablets.The changes of IBS symptom severity scale(IBS-SSS),hospital anxiety and depression scale(HADS),IBS quality of life scale(IBS-QOL)and serum 5-hydroxytryptamine(5-HT)were compared between the two groups before and after treatment.The clinical efficacy and recurrence rate after treatment were evaluated.Results:After treatment,the IBS-SSS and H ADS scores of the two groups decreased,the IBS-QOL score increased,and the serum 5-HT content decreased(P＜0.05 or P＜0.01),and the improvement of the observation group was significantly better than that of the control group(P＜0.05).Compared with the control group,the total effective rate of the observation group was higher,and the recur-rence rate was lower(P＜0.05).Conclusion:The curative effect of scraping and detoxifying therapy of Zhuang medicine in the treatment of IBS-D is better,which can improve the gastrointestinal symptoms of patients,inhibit the pain medium as its main mechanism of action,and the recurrence rate is low,with few side effects.
Diarrhea-predominant irritable bowel syndrome(IBS-D)Scraping and detoxification therapy of Zhuang medicine5-HTClinical observation
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