Study on Medicine Syndrome Types and Medication Regularity of Traditional Chi-nese Medicine for Treatment of Optic Neuritis Based on the Ancient and Modern Medical Case Cloud Platform
OBJECTIVE To explore the Traditional Chinese Medicine(TCM)syndrome types and medication rules of optic neuritis(ON)based on the ancient and modern medical case cloud platform.METHODS Medical records and literature on the treatment of optic neuritis with TCM were included from the establishment of the database to December 31st,2022,on the ancient and modern medical case cloud platform,CNKI,Wanfang Data,VIP,and SinoMed.Input TCM syndrome types,prescription composition,and treatment methods into Excel software and establish a database.After standardizing the names of Chinese medicines,the data mining module of the ancient and modern medical case cloud platform(V2.3.5)was used to analyze TCM syndrome types,four Qi,five flavors,attributes,frequency statistics of high-frequency medicines,cluster analysis,and complex network analysis.RESULTS(1)General information:A total of 15 medical records and 110 works of literature were included,covering 68 syndrome types,"Liver stagnation and Qi stagnation syndrome"(28 times,12.02%)appeared most frequently,with 233 prescriptions,involving 211 kinds of Chinese medicines,with a total of 2,579 frequencies.The medicine properties were mainly cold(49 medicines,23.22%),the flavors were mainly sweet(76 medicines,36.02%),and liver meridian is the most common in terms of the meridian tropisms(73 medicines,34.60%).(2)Frequency statistics of high-frequency medicines:There were 21 Chinese medicines with a frequency of medication more than 30 times and the top five were Angelica Sinensis(165 times,70.82%),Poria cocos(143 times,61.37%),Radix Bupleuri(127 times,54.51%),Radix Paeoniae Alba(118 times,50.64%),and Atractylodes macrocephala(110 times,47.21%).(3)Cluster analysis of high-frequency Chinese medicines:The association rule analysis yielded 8 core Chinese medicines pairs,the top five were"Radix Paeoniae Alba-Angelica sinensis","Radix Bupleuri-Angelica sinensis","Atractylodes macrocephala-Angelica sinensis""Atractylodes macrocephala-Poria cocos""Radix Paeoniae Alba-Poria cocos".(4)Correlation analysis of high-frequency Chinese medicines:Cluster analysis resulted in four Chinese medicines combinations,with the functions of clearing heat,cooling blood and activating blood circulation,soothing liver,strengthening spleen and replenishing Qi,nourishing Yin,clearing heart and cooling blood,tonifying kidney,replenishing Qi and removing dampness.(5)Complex network analysis:The core prescription extracted is Danzhi Xiaoyao Powder plus or minus,covering ten Chinese medicines.CONCLUSIONS The TCM syndrome differentiation of ON is closely related to liver.TCM treatment of ON is mainly to regulate liver,adopting the methods of soothing liver,clearing liver and nourishing liver,it also takes into account heart and spleen and nourishes Qi and blood.
Traditional Chinese Medicineoptic neuritisancient and modern medical case cloud platformmedication rules
NETL
NSTL
万方数据
维普
