Excavating the Medication Rule of Traditional Chinese Medicine in Treating Chil-dren with Chalazion based on Support Platform of TCM Inheritance
OBJECTIVE To explore the prescription patterns of Traditional Chinese Medicine(TCM)in the treatment of chalazion in children based on the TCM Inheritance Assisting Platform.METHODS Relevant literature on TCM treatment of chalazion in children was collected from the China National Knowledge Infrastructure(CNKI),Wanfang Data,and VIP databases from the establishment of the databases to November 2022.The collected prescriptions were input into the TCM Inheritance Assisting Platform(V3.0),and after standardizing the names of Chinese medicines,the properties,frequency of use,and therapeutic effects of Chinese medicines were analyzed.RESULTS(1)General Information:A total of 57 prescriptions met the criteria,involving 151 different Chinese medicines with a cumulative frequency of use of 582 times.Among these Chinese medicines,cold-natured Chinese medicines were the most commonly used(69 medicines,45.92%),bitter-taste Chinese medicines were the most prevalent among the five tastes(54 medicines,35.92%),and the lung meridian was the most commonly associated meridian(41 medicines,27.27%).(2)High-frequency Chinese medicines usage:There were 12 high-frequency Chinese medicines with usage frequencies≥12 times.The top five are Pericarpium Citri Reticulatae(29 times,4.98%),Pinellia ternata(26 times,4.47%),Poria cocos(26 times,4.47%),Glycyrrhiza uralensis Fisch(24 times,4.12%)and Forsythia suspensa(17 times,2.92%).(3)Classification of high-frequency Chinese medicines therapeutic effects:The most common therapeutic effect was heat-clearing Chinese medicines(138 times,23.71%),followed by phlegm-resolving and cough-suppressing Chinese medicines(60 times,10.30%),exterior-releasing Chinese medicines(54 times,9.27%),tonifying Chinese medicines(44 times,7.56%),and Qi-regulating Chinese medicines(40 times,6.87%).(4)Cluster analysis of high-frequency herb effects:A total of six categories of prescription effects were identified,including tonifying Qi and strengthening spleen,drying dampness and resolving phlegm,promoting digestion and resolving stagnation,heat-clearing and detoxifying,improving vision and dispersing phlegm,and calming liver and quelling wind.(5)Association rule analysis of high-frequency Chinese medicines:The five strongest associations were found between Pericarpium Citri Reticulatae-Poria cocos,Pericarpium Citri Reticulatae-Pinellia ternata,Pinellia ternata-Glycyrrhiza uralensis Fisch,Pericarpium Citri Reticulatae-Bombyx Batryticatus,Pericarpium Citri Reticulatae-Forsythia suspensa.CONCLUSIONS TCM treatment for chalazion in children primarily involves heat-clearing and detoxification,resolving phlegm and dispersing masses,and is supplemented with Qi-tonifying and liver-calming herbs.This study provides a reference for clinicians in terms of medication and treatment strategies.
chalazionmeibomian gland cystchalazion granulomaTraditional Chinese Medicine treatmentdata miningTraditional Chinese Medicine inheritance assisting platformcompatibility patterns
NETL
NSTL
万方数据
维普
