Clinical Study on Mupian Qianzheng Decoction Combined with Acupuncture in Treat-ing Eye Deviation
OBJECTIVE To investigate the therapeutic effects of Mupian Qianzheng Decoction combined with acupuncture in the treatment of ocular deviation and provide clinical insights for its management.METHODS A total of 122 patients with ocular deviation admitted to the Ophthalmology Department of Chongqing Hospital of Traditional Chinese Medicine from June 2019 to June 2022 were included in the study.They were randomly divided into the observation group(OG)with 62 patients and the control group(CG)with 60 patients.The control group received treatment focusing on nutritional support for nerves,improvement of microcirculation,and basic disease management.The observation group,in addition to the treatment provided to the control group,received additional oral administration of Mupian Qianzheng Decoction combined with acupuncture.Each treatment cycle lasted for 10 days,with a total of three cycles observed.The degree of restricted eye movement,ffusional image inspection,and prism strabismus angle degreeuin two groups were observed.RESULTS Before treatment,there were no statistically significant differences between the two groups in terms of the degree of restricted eye movement,fusional image inspection,and prism strabismus angle(P>0.05).(1)Comparison of degree of restricted eye movement:The degree of restricted eye movement in both groups decreased significantly after treatment compared to before treatment(ZOG=-6.710,P=0.000;ZCG=-2.953,P= 0.003).Post-treatment comparison between the two groups revealed that the observation group had a lower degree of restricted eye movement than the control group,with statistically significant differences(Z=-4.523,P=0.000).(2)Comparison of fusional image inspection:The fusional image separation in the maximum direction decreased significantly in both groups after treatment compared to before treatment(ZOG=-8.266,ZCG=-4.168,both P=0.000).When comparing the two groups after treatment,the observation group exhibited a smaller fusional image separation in the maximum direction than the control group,with statistically significant differences(Z=-5.331,P= 0.000).(3)Comparison of prism strabismus angle degree:The prism strabismus angle in both groups decreased significantly after treatment compared to before treatment(ZOG=-8.348,P=0.000;ZCG=-2.850,P=0.004).Post-treatment comparison between the two groups revealed that the observation group had a lower prism strabismus angle degree than the control group,with statistically significant differences(Z=-6.430,P=0.000).(4)Clinical efficacy:The overall effective rate in the observation group(100.00%)was higher than that in the control group(78.33%),and the difference was statistically significant(χ2=15.035,P=0.000).Specifically,for the treatment of oculomotor nerve paralysis,the overall effective rate in the observation group(100.00%)was higher than that in the control group(84.62%),and the difference was statistically significant(P= 0.041).However,there was no statistically significant difference between the two groups in the overall effective rates for abducent nerve paralysis and trochlear nerve paralysis(P>0.05).CONCLUSIONS The combination of Mupian Qianzheng Decoction with acupuncture can improve restricted eye movement,fusional symptoms,and overall clinical efficacy in the treatment of ocular deviation.The treatment regimen demonstrates particularly favorable outcomes in cases of oculomotor nerve paralysis.
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