Research Progress on the Intervention of Chinese Medicine Monomers in Proliferative Vitreoretinopathy
Proliferative vitreoretinopathy(PVR)is a major cause of surgical failure and recur-rence in rhegmatogenous retinal detachment.Current clinical treatments for PVR mainly rely on surgery,but they have certain limitations.Therefore,it is necessary to explore new medicine thera-pies.Chinese medicine monomers,with the dual advantages of Chinese medicine and chemical medicines,have become a research focus,particularly in the protection of the retina in PVR treat-ment.This article reviews the literature on the treatment of PVR with Chinese medicine monomers in recent years.It was found that monomers such as curcumin,saffron,and quercetin can lower the expression of platelet-derived growth factor,transforming growth factor,epidermal growth factor,and other factors.They inhibit the biological process of epithelial-mesenchymal transition,prevent-ing the occurrence of PVR.The discovery of these Chinese medicine monomers provides new op-tions for the development of novel medicines and offers a more diversified approach to the treat-ment of PVR.
proliferative vitreoretinopathyChinese medicine monomersretinal pigment epi-thelial cellspathological mechanism
NETL
NSTL
万方数据
维普
