Research on the Medication Rules of Traditional Chinese Medicine in the Treatment of Postoperative Glaucoma based on Data Mining
OBJECTIVE To analyze the medication rules of Traditional Chinese Medicine(TCM)in the treatment of postoperative glaucoma using data mining techniques.METHODS The literatures related to the treatment of postoperative glaucoma with TCM were collected from the China National Knowledge Infrastructure(CNKI),Wanfang Data,and VIP databases from the establishment of the databases until August 31st,2022.After standardizing and unifying the names of the Chinese medicines involved,the data were entered into an Excel database.SPSS Modeler 18.0 and SPSS Statistics 26.0 software were used to perform association rule and clustering analyses on the processed data.RESULTS(1)General information:A total of 57 articles were included,comprising 64 prescriptions and involving 113 different Chinese medicines,with a cumulative frequency of 703 times.The medicine properties were mainly cold(50 medicines,44.25%),the five flavors were mainly sweet(46 medicines,40.71%),and the pertained meridians were mostly liver meridian(42 medicines,37.17%).(2)Frequency of usage of high-frequency Chinese medicines:There are 21 medicines of high frequency Chinese medicines,with the top five are Radix Angelicae Sinensis(43 times,6.12%),Rhizoma Ligustici Chuanxiong(42 times,5.97%),Radix Salviae Miltiorrhizae(33 times,4.69%),Poria(27 times,3.84%)and Radix Astragali seu Hedysari(26 times,3.70%).(3)Effects classification of high-frequency Chinese medicines:The tonic medicines were the most frequently used(six medicines,28.57%),followed by blood-activating and stasis-removing medicines(five medicines,23.81%),dampness-eliminating medicines(three medicines,14.29%),heat-clearing medicines(three medicines,14.29%)and exterior-releasing medicines(two medicines,9.52%).(4)Cluster analysis of high-frequency Chinese medicines:Two cluster prescriptions were obtained,with the following effects,tonifying Qi,activating blood,promoting diuresis,and promoting Qi,activating blood,promoting diuresis.(5)Correlation analysis of high-frequency Chinese medicines:The five combinations with high correlation are Rhizoma Atractylodis Macrocephalae-Poria,Radix Astragali seu Hedysari-Lumbricus,Rhizoma Ligustici Chuanxiong-Semen Persicae,Radix Salviae Miltiorrhizae-Radix Puerariae and Radix Angelicae Sinensis-Radix Paeoniae Alba.CONCLUSIONS The TCM treatment of postoperative glaucoma primarily focuses on liver meridian,with an emphasis on tonifying Qi or promoting Qi,often combined with blood activating and diuretic Chinese medicines.
postoperative glaucomadata miningTraditional Chinese Medicinemedication rules
NETL
NSTL
万方数据
维普
