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八宝眼膏治疗早期麦粒肿的临床观察

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目的 观察八宝眼膏治疗早期麦粒肿(急性睑腺炎)的临床疗效.方法 纳入2021年9月—2023年3月在北京中医药大学东方医院眼科就诊的早期麦粒肿患者60例(60只眼).随机分为试验组和对照组,试验组有1例脱落,最终纳入对照组30例(30只眼),试验组29例(29只眼).试验组予八宝眼膏点眼,对照组予妥布霉素眼膏点眼.2组均观察14 d.分别于治疗前、后记录视觉模拟评分(VAS)评分、症状积分,测量麦粒肿肿块直径,评价临床疗效.结果 2组治疗前VAS评分、症状积分、肿块直径比较,差异均无统计学意义(P>0.05).(1)VAS评分:2组治疗后VAS评分均较治疗前减少,差异均有统计学意义(Z试验组=-4.750、Z对照组=-4.858,均P=0.000),治疗后2组组间比较,试验组VAS评分优于对照组,差异有统计学意义(Z=-2.572,P=0.010).(2)症状积分:治疗后2组症状积分均较治疗前减少,差异均有统计学意义(Z试验组=-4.718、Z对照组=-4.715,均P=0.000).2组间比较,试验组症状积分改善优于对照组,差异有统计学意义(Z=-2.782,P =0.005).(3)肿块直径:治疗后2组肿块直径均较治疗前减小,差异均有统计学意义(Z试验组=-4.704、Z对照组=-4.783,均P= 0.000).治疗后2组间比较,试验组肿块直径减小优于对照组,差异有统计学意义(Z=-2.541,P=0.011).(4)临床疗效:试验组总有效率较对照组,差异无统计学意义(P>0.05).结论 八宝眼膏治疗早期麦粒肿安全有效,具有一定的临床推广应用价值.
Observation on the Therapeutic Effect of Babao Eye Ointment in the Treatment of Early Hordeolum
OBJECTIVE To observe the clinical efficacy of Babao eye ointment in treating early hordeolum(acute meibomian gland inflammation).METHODS A total of 60 patients(60 eyes)with early hordeolum treated in Dongfang Hospital of Beijing University of Chinese Medicine from September 2021 to March 2023,were included in the study.They were randomly divided into the experiment group and the control group.One participant dropped out from the experiment group,resulting in 30 cases in the control group(30 eyes)and 29 cases(29 eyes)in the experiment group.The experiment group was treated with Babao eye ointment,while the control group was treated with Tobramycin eye ointment.Both groups were observed for 14 days.VAS,symptom scores,and the diameter of the Hordeolum were recorded before and after treatment to evaluate the clinical efficacy.RESULTS There were no statistically significant differences in VAS,symptom scores,and Hordeolum diameter between the two groups before treatment(P>0.05).(1)VAS:Both groups showed a significant decrease in VAS after treatment compared to before treatment(ZEG =-4.750,ZCG =-4.858,both P = 0.000).The experiment group had a better VAS than the control group after treatment,with a statistically significant difference(Z =-2.572,P= 0.010).(2)Symptom scores:Both groups showed a significant decrease in symptom scores after treatment compared to before treatment(ZEG=-4.718,ZCG =-4.715,both P = 0.000).The improvement in symptom scores in the experiment group was better than that in the control group,with a statistically significant difference(Z=-2.782,P=0.005).(3)Hordeolum diameter:Both groups showed a significant decrease in hordeolum diameter after treatment compared to before treatment(ZEG=-4.704,ZCG=-4.783,both P = 0.000).The reduction in hordeolum diameter in the experiment group was better than that in the control group after treatment,with a statistically significant difference(Z =-2.541,P = 0.011).(4)Clinical efficacy:The total effective rate in the test group was higher than that in the control group,but the difference was not statistically significant(P>0.05).CONCLUSIONS Baoban eye ointment is safe and effective in the treatment of early granuloma,and has certain value for clinical promotion and application.

Babao eye ointmenthordeolumacute palpebral gland inflammation

于欣宁、李朝妍、闫晓玲、夏燕婷、郝美玲、罗现科、杨昌璐、周剑

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北京中医药大学,北京 100029

北京中医药大学东方医院,北京 100078

八宝眼膏 麦粒肿 急性睑腺炎

北京中医药大学东方医院横向课题

hx202113

2024

中国中医眼科杂志
中国中医科学院

中国中医眼科杂志

CSTPCD
影响因子:0.476
ISSN:1002-4379
年,卷(期):2024.34(4)
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