摘要
干燥综合征相关性干眼(SS-DED)是指干燥综合征侵犯泪腺时继发的干眼,可导致泪膜渗透压增加和眼表炎症.非感染性炎症是影响SS-DED发生和发展的重要因素,抗炎是该病的重要治疗手段.本文通过查阅SS-DED相关文献,从西医发病机制、病理改变、西医治疗、中医病因病机、中医治疗等方面予以总结,发现西医的主要治疗药物包括人工泪液、抗炎药物及物理疗法,中医药则通过辨证论治、针灸等治疗也可有效抑制SS-DED的眼表炎症,恢复眼表免疫稳态平衡,有一定的临床优势.本研究可为干燥综合征相关性干眼的诊治和后续研究提供参考.
Abstract
Dry eye syndrome associated with Sjögren's syndrome(SS-DED)refers to dry eye syndrome that occurs as a result of involvement of the lacrimal glands in Sjögren's syndrome,lead-ing to increased tear film osmolarity and ocular surface inflammation.Non-infectious inflammation is an important factor influencing the occurrence and development of SS-DED,and anti-inflammatory treatment is a key therapeutic approach for this condition.This article summarizes the research progress in SS-DED from both Western Medicine and Traditional Chinese Medicine(TCM)perspectives,including the pathogenesis,pathological changes,treatment approaches in Western Medicine,and etiology,pathogenesis,and treatment in TCM.It is found that the main treatment modalities in Western Medicine include artificial tears,anti-inflammatory drugs,and physical therapy.TCM,on the other hand,utilizes treatment methods such as individualized diag-nosis and treatment based on syndrome differentiation,acupuncture,and herbal medicine to effec-tively suppress ocular surface inflammation in SS-DED and restore ocular immune homeostasis,demonstrating certain clinical advantages.This study provides valuable insights for the diagnosis and treatment of SS-DED and future research directions.
国家科技期刊平台
NSTL
维普
万方数据