There have been numerous reports in recent years regarding uveitis induced by biologic agents.This paper systematically reviews the literature on uveitis induced by biologic agents and summarizes the clinical characteristics.It is found that the biologic agents currently causing uveitis mainly include five categories:Tumor necrosis factor-α(TNF-α)inhibitors,anti-vascular endothelial growth factor(VEGF)agents,immune checkpoint inhibitors,B-Raf proto-oncogene(BRAF)and mitogen-activated protein kinase(MEK)inhibitors,and injectable vaccines.These agents are commonly used to treat conditions such as rheumatoid arthritis,tumors,ankylos-ing spondylitis,uveitis,among others,with patients ranging in age from one month to 92 years and onset times varying from one day to six years post-medication.Current limited evidence suggests that TNF-α inhibitors are more prone to inducing uveitis.The type of uveitis induced by biologic agents is mainly anterior uveitis,and there is a tendency for recurrence.With steroid and mydri-atic treatment and cessation of biologic agent use,the visual prognosis of most patients with in-duced uveitis is good.
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