Research Progress on the Basic Intervention of Baicalin and Baicalein in Ocular Dis-eases
Flavonoid compounds baicalin and baicalein are two important active components of Chinese medicine Scutellaria baicalensis,possessing anti-inflammatory,antioxidant,and anti-bacterial pharmacological properties.The basic research on their intervention in ocular diseases has been increasing annually.This article reviews the recent progress in the basic research on the intervention of baicalin and baicalein in ocular diseases.The diseases involved include corneal in-jury,cataract,diabetic retinopathy,glaucoma,uveitis,age-related macular degeneration,and isch-emic retinopathy.The primary mechanisms of action are through modulating inflammatory re-sponses,reducing oxidative stress,and inhibiting bacterial infections,indicating that baicalin and baicalein have potential therapeutic value for ocular diseases.This research provides theoretical support for the clinical application of baicalin and baicalein and offers insights for the application of Scutellaria baicalensis in ophthalmic pharmaceuticals and health products.
万方数据
维普
