Study on Traditional Chinese Medicine Syndrome Elements Characteristics of Ante-rior Uveitis
OBJECTIVE To investigate and summarize the characteristics of syndrome elements of anterior uveitis(AU)in Traditional Chinese Medicine(TCM)literature,providing references for standardized clinical syndrome differentiation and treatment of AU.METHODS Relevant TCM syndrome type literature on AU published in CNKI,Wanfang,and VIP databases from their inception to March 31st,2023,was collected.TCM syndrome names were standardized and the syndromes were deconstructed.The syndrome entries and case numbers extracted from the literature were compiled into an Excel database.Frequency and frequency descriptive analyses were conducted on disease location and disease nature syndrome elements.Systematic cluster analysis and association rule analysis were performed on the syndrome elements.RESULTS(1)General information:A total of 24 articles were included,with a total of 1,685 cases.(2)Distribution of syndromes and syndrome elements:The top five syndromes were liver meridian wind-heat(329 times,19.53%),excessive liver-gallbladder fire(224 times,13.29%),hyperactivity of liver fire(205 times,12.17%),Yin deficiency with effulgent fire(166 times,9.85%),and damp-heat in liver and gallbladder(94 times,5.58%).(3)Characteristics of syndrome elements:There were five disease location elements,ranked by frequency:Liver(1,035 times,61.42%),gallbladder(335 times,19.88%),exterior(163 times,9.64%),kidney(117 times,6.94%),and spleen(55 times,3.26%).There were 13 types of disease nature elements,with heat being the most frequent(1,447 times,85.88%).In the classification analysis of deficiency and excess,excess syndrome elements appeared 2,458 times(76.42%),while deficiency syndrome elements appeared 758 times(23.56%).Among excess syndrome elements,heat was the most frequent(1,447 times,44.99%),and Yin deficiency was the most frequent among deficiency syndrome elements(374 times,11.63%).(4)Association rule analysis of syndrome elements:Eight strong association rules were identified,including five two-item strong association rules and three three-item strong association rules,inferring five basic syndromes:Hyperactivity of liver fire,wind-heat syndrome,damp-heat syndrome,excessive liver-gallbladder fire,and liver meridian wind-heat syndrome.The association rule network diagram showed the strongest association between liver and heat,inferring the basic syndrome as hyperactivity of liver fire.CONCLUSIONS Liver meridian wind-heat,excessive liver-gallbladder fire,and hyperactivity of liver fire are the main syndromes in anterior uveitis patients.the important disease location element in anterior uveitis is liver,and the important disease nature element is heat,with a predominance of excess syndromes.
anterior uveitissyndrome elementssyndrome differentiation and treatmentlit-erature study
万方数据
维普
