Research Progress on Curcumin and Its Nanoformulations in Glaucoma
Curcumin,an active monomer extracted from Chinese medicines such as tur-meric,zedoary,and curcuma,exhibits multiple pharmacological actions and low toxicity.Various nanoformulations of curcumin have been developed,showing promising clinical application pros-pects.Recent studies have found that curcumin possesses neuroprotective properties,which may aid in the prevention and treatment of glaucoma.This paper summarizes the applications and phar-macological mechanisms of curcumin and its nanoformulations in glaucoma,including anti-inflammatory,antioxidant,anti-ischemia-reperfusion,anti-fibrosis,anti-glutamate toxicity,and modulation of autophagy.These findings may provide theoretical references for the future preven-tion and treatment of glaucoma.
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