Research Progress on the Treatment of Proliferative Vitreoretinopathy with Tradi-tional Chinese Medicine
Proliferative vitreoretinopathy(PVR)is a major cause of surgical failure and recur-rence in rhegmatogenous retinal detachment.Currently,Western Medicine primarily relies on sur-gery for treatment,but there are limitations.Traditional Chinese Medicine(TCM)treatment of PVR has become a research hotspot.This article aims to review recent advances in both Western Medicine and TCM understanding of PVR.It summarizes and categorizes relevant literature on the efficacy of single Chinese medicine and compound formulations that have been proven effective in prevention and treatment.It is found that PVR is closely related to the functional status of organs such as liver,spleen,and kidney,providing a theoretical basis for the application of TCM in PVR treatment.Meanwhile,single Chinese medicine such as saffron acid,total saponins of Panax no-toginseng,and artemether,as well as compound formulations such as Huoxue Sanjie Decoction,Sanxue Mingmu Tablet,and Dahuang Zhechong Pill,can inhibit biological processes such as pro-liferation,migration,and epithelial-mesenchymal transition of retinal pigment epithelial cells through multiple signaling pathways,thereby preventing and treating PVR.These studies provide a scientific basis for TCM in preventing and treating PVR,indicating the potential and advantages of TCM in PVR treatment.
Traditional Chinese Medicineproliferative vitreoretinopathyresearch progress