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互联网从业人员干眼中医证候证素分布特点研究

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目的 研究互联网从业人员干眼的中医证型及证候要素分布规律,以及其与年龄、性别、眼部主症之间的相关性.方法 随机整群抽样2018年11月—2018年12月北京市某大型互联网公司中青年员工613例,筛查确诊为干眼患者356例,由专人对干眼患者进行中医证候评估访谈,填写中医证候量表;将患者的症状、体征、舌脉信息等依据证候辨证素量表提取,诊断相应证素.分析纳入病例的中医证型、证候要素分布情况,以及年龄、性别、眼部主症与中医证型之间的关系.结果 (1)中医证型:248例互联网从业干眼患者的中医证型从高到低依次为气阴两虚证(65例,26.21%)、肝肾阴虚证(55例,26.18%)、肺阴不足证(51例,20.56%)、脾气亏虚证(35例,14.11%)、阴虚湿热证(22例,8.87%)、肝经郁热证(20例,8.06%).(2)证素:共提取得到核心证素8项.其中,病性证素5项,从高到低依次为阴虚(205例,82.66%)、气虚(121例,48.79%)、气滞(110例,44.35%)、热蕴(91例,36.69%)、内湿(60例,24.19%);病位证素3项,从高到低依次为肝(138例,55.65%)、肺(68例,27.42%)、肾(57例,22.98%).(3)性别:6种中医证型的互联网从业干眼患者的性别占比比较,差异无统计学意义(P>0.05).(4)年龄:不同年龄段的肝肾阴虚证患者占比比较,差异有统计学意义(χ2=13.215,P=0.001),干眼患者的占比随年龄增长逐渐升高.不同年龄段之间气阴两虚证、肺阴不足证、脾气亏虚证、阴虚湿热证、肝经郁热证的占比比较,差异无统计学意义(P>0.05).(5)眼部主症:248例干眼患者均有2种以上眼部主症,从高到低依次为疲劳感(229例,92.34%)、干涩感(222例,89.52%)、异物感(128例,51.61%)、视力波动(100例,40.32%)、烧灼感(93例,37.50%).其中,疲劳感和干涩感的不同中医证型占比比较,差异均有统计学意义(χ2疲劳感=14.687,P=0.012;χ2干涩感=11.285,P=0.046).结论 互联网从业者干眼的中医证型以气阴两虚最多见,证候要素以阴虚、肝最多见;年龄与干眼的中医证型有相关性,性别对干眼辨证无明显影响;眼部主症以疲劳感最多见,且有无疲劳感对干眼辨证有一定影响.
Study on the Distribution Characteristics of Traditional Chinese Medicine Syndrome Elements in Dry Eye among Internet Industry Workers
OBJECTIVE To investigate the distribution patterns of Traditional Chinese Medicine(TCM)syndrome types and syndrome elements in dry eye among internet industry workers,and explore their correlation with age,gender,and primary ocular symptoms.METHODS A random cluster sampling was conducted from November to December 2018,involving 613 young and middle-aged employees from a large internet company in Beijing.A total of 356 dry eye patients were diagnosed,and TCM syndrome assessment interviews were conducted by trained personnel using a TCM syndrome scale.The symptoms,signs,tongue,and pulse information of the patients were extracted according to the syndrome differentiation scale to determine the corresponding syndrome elements.The distribution of TCM syndrome types and syndrome elements,and their relationship with age,gender,and primary ocular symptoms were analyzed.RESULTS(1)TCM syndrome types:Among 248 dry eye patients in the internet industry,the most common TCM syndrome types were Qi and Yin deficiency syndrome(65 cases,26.21%),liver and kidney Yin deficiency syndrome(55 cases,26.18%),lung Yin deficiency syndrome(51 cases,20.56%),spleen Qi deficiency syndrome(35 cases,14.11%),Yin deficiency with damp-heat syndrome(22 cases,8.87%),and liver Qi stagnation with heat syndrome(20 cases,8.06%).(2)Syndrome elements:A total of eight core syndrome elements were extracted.Among them,the pathogenic elements(in descending order)were Yin deficiency(205 cases,82.66%),Qi deficiency(121 cases,48.79%),Qi stagnation(110 cases,44.35%),heat accumulation(91 cases,36.69%),and internal dampness(60 cases,24.19%).The location of the disease elements(in descending order)were liver(138 cases,55.65%),lung(68 cases,27.42%),and kidney(57 cases,22.98%).(3)Gender:The gender distribution among the six TCM syndrome types in dry eye patients in the internet industry showed no significant statistical differences(P>0.05).(4)Age:The comparison of the proportion of patients with liver and kidney Yin deficiency syndrome across different age groups showed statistically significant differences(χ2=13.215,P=0.001),with the proportion of dry eye patients increasing with age.There were no significant differences in the proportions of Qi and Yin deficiency syndrome,lung Yin deficiency syndrome,spleen Qi deficiency syndrome,Yin deficiency with damp-heat syndrome,and liver Qi stagnation with heat syndrome across different age groups(P>0.05).(5)Primary ocular symptoms:All 248 dry eye patients had more than two primary ocular symptoms,with the most common being fatigue(229 cases,92.34%),dryness(222 cases,89.52%),foreign body sensation(128 cases,51.61%),visual fluctuation(100 cases,40.32%),and burning sensation(93 cases,37.50%).Among these,the comparison of the proportions of different TCM syndrome types in relation to fatigue and dryness showed statistically significant differences(χ2fatigue=14.687,P=0.012;χ2dryness=11.285,P=0.046).CONCLUSIONS The most common TCM syndrome type in dry eye among internet workers is Qi and Yin deficiency,with Yin deficiency and liver being the most frequent syndrome elements.Age is correlated with the TCM syndrome type of dry eye,while gender does not significantly affect syndrome differentiation.Fatigue is the most common ocular symptom,and the presence or absence of fatigue has a certain impact on syndrome differentiation in dry eye.

dry eyeTraditional Chinese Medicine syndromesyndrome elementsinternet industry workerslocal syndrome differentiation

梁子钰、何萍、吴鲁华、龙子弋、孟欢、王志强

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北京中医药大学第三附属医院,北京 100029

北京中医药大学东直门医院,北京 100700

干眼 中医证候 证素 互联网从业者 局部辨证

2024

中国中医眼科杂志
中国中医科学院

中国中医眼科杂志

CSTPCD
影响因子:0.476
ISSN:1002-4379
年,卷(期):2024.34(12)