《职业性三氯乙烯药疹样皮炎诊断标准》修订说明
Introduction to the revision of Diagnostic Standard for Occupational Medicamentose-like Dermatitis due to Trichloroethylene
夏丽华 1张莹 1邓小峰 1周珊宇 1黄永顺 1李喜英 1吴奇峰 1蔡木蔚 2罗孝文 3赵风玲4
作者信息
- 1. 广东省职业病防治院,广东广州 510300
- 2. 东莞市第六人民医院(东莞市职业病防治中心),广东东莞 523008
- 3. 深圳市职业病防治院,广东深圳 518020
- 4. 河南省职业病防治研究院,河南郑州 450052
- 折叠
摘要
随着临床相关学科的发展,国内外相关标准/指南的更新和建立,GBZ 185-2006《职业性三氯乙烯药疹样皮炎诊断标准》(以下简称"GBZ 185-2006")已不能满足临床需求.基于循证医学原则,依据有关法律法规和相关标准/指南,系统梳理国内外的职业性三氯乙烯药疹样皮炎(OMDT)的研究资料,并结合前期临床实践和临床相关学科的发展,对GBZ 185-2006进行修订.主要修改内容包括:增加了 OMDT的术语与定义,调整了诊断原则中关于临床表现的表述,调整了潜伏期,删除了发病概率的诊断要求,增加了特异性变应原斑贴试验为病因学诊断指标,规范了特异性变应原斑贴试验的适用范围、操作方法与注意事项.此外,亦完善了附录A的"三氯乙烯药疹样皮炎皮肤损害的基本特点和临床类型"相关内容,修订处理原则,增加了治疗技术新进展——人工肝应用的内容.修订后的GBZ 185-2024《职业性三氯乙烯药疹样皮炎诊断标准》具有较强的科学性和可操作性,可为医疗卫生机构规范诊断和处理OMDT提供技术依据.
Abstract
With the development of clinical related disciplines,the update and establishment of relevant standards/guidelines at home and abroad,GBZ 185-2006 Diagnostic Criteria for Occupational Medicamentose-like Dermatitis due to Trichloroethylene(hereinafter referred to as"GBZ 185-2006")was unable to meet clinical needs.Therefore,the GBZ 185-2006 was revised based on the principles of evidence-based medicine,in accordance with relevant laws/regulations and relevant standards/guidelines in combination with review of research data on occupational medicamentose-like dermatitis due to trichloroethylene(OMDT)home and abroad,and the development of clinical practice and clinical related disciplines.The main modifications include:adding terms and definitions of OMDT,modifying the description of clinical manifestations of the diagnostic principles,adjusting the description of latency,deleting the diagnostic requirement of the incidence probability,adding the specific allergen patch test as the etiological diagnostic index,standardizing the application scope,operating procedure and precautions of the specific allergen patch test.In addition,the relevant content of"Basic Characteristics and Clinical Types of Skin Damage of Medicamentose-like Dermatitis due to Trichloroethylene"in Appendix A is improved,the treatment principles are revised,and the content of new progress in treatment,artificial liver application,are added.The revised GBZ 185-2024 Diagnostic Standard for Occupational Medicamentose-like Dermatitis due to Trichloroethylene is more scientific and practical,and can provide technical basis for the standardized diagnosis and treatment of OMDT in medical and health institutions.
关键词
三氯乙烯药疹样皮炎/诊断/标准/修订/斑贴试验/编制说明Key words
Medicamentose-like dermatitis due to trichloroethylene/Diagnosis/Standard/Revision/Patch test/Preparation instruction引用本文复制引用
基金项目
卫生标准修订计划项目(中疾控标准便函[2021]881号)
国家临床重点专科建设项目(2011-09)
出版年
2024
NETL
NSTL
万方数据