Analyzing the clinical characteristics of 56 cases of occupational pneumoconiosis complicated with interstitial lung disease
Objective To explore the clinical features of occupational pneumoconiosis(hereinafter referred to as"pneumoconiosis")complicated with interstitial lung disease(ILD).Methods A total of 56 patients with pneumoconiosis complicated with ILD were selected as the research subjects using a retrospective study method,and their clinical features were analyzed.Results The main clinical symptoms of the 56 patients were progressive dyspnea,cough,and expectoration,with detection rates of 76.8%,75.0%,and 55.4%,respectively.The detection rates of hypoxemia and respiratory failure were 67.9%and 32.1%respectively.Among the 35 patients who underwent pulmonary function test,restrictive,mixed,and obstructive ventilatory disorders were detected in 37.1%,22.9%,and 17.1%of cases,respectively,with a 74.3%detection rate for reduced diffusion capacity.High resolution computed tomography of the chest revealed ground-glass shadows,grid shadow,interlobular thickening,honeycomb shadows and tractive bronchiectasis,with detection rates of 57.1%,35.7%,35.7%,23.2%,and 17.9%,respectively.Lesions were mostly diffusely distributed in both lungs,with a predominance in the lower lungs compared to the mid-upper lungs.Patients complicated with connective tissue disease,including systemic sclerosis,rheumatoid arthritis,systemic lupus erythematosus,polymyositis,and dermatomyositis,accounted for 33.9%(19 cases).Conclusion The clinical symptoms,pulmonary function,and arterial blood gas analysis results of patients with pneumoconiosis complicated with ILD show no specific features.However,a subset of pneumoconiosis patients with ILD also have coexisting connective tissue diseases.
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