Research Progress on Pharmacological Effects of Atractylenolides from Atractylodes Macrocephala in Recent Ten Years
Rhizoma macrocephala,as a traditional Chinese medicine,was first recorded in Shennong Classic of Materia Medica.It has a long history of medicinal use and rich medicinal value.Based on relevant research,it was found that atractylenolides contained in Rhizoma macrocephala,have a great relationship with the medicinal effects including malignant tumors,neuronal apoptosis,gastroin-testinal inflammatory,liver fibrosis,and other diseases.In this study,the chemical structure and pharmacological studies of atractyle-nolides contained in Rhizoma macrocephala were summarized.Atractylenolide Ⅰ,atractylenolide Ⅱ,and atractylenolide Ⅲ were fre-quently studied and identified as active components.The investigation of atractylenolides contained in Rhizoma macrocephala pro-vides new strategies for the treatment of intractable diseases such as Alzheimer's disease and malignant tumors.
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